The thermal structural transition of α-crystallin inhibits the heat induced self-aggregation.

α-crystallin, the major constituent of human lens, is a member of the heat-shock proteins family and it is known to have a quaternary structural transition at . The presence of calcium ions and/or temperature changes induce supramolecular self-aggregation, a process of relevance in the cataractogene...

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Autores principales: Giuseppe Maulucci, Massimiliano Papi, Giuseppe Arcovito, Marco De Spirito
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/43afa2aea000458982e379eaffbebab5
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