The receptor PTPRU is a redox sensitive pseudophosphatase

Receptor-linked protein tyrosine phosphatases (RPTPs) usually contain an active membrane proximal domain and an inactive pseudophosphatase domain. Here, the authors characterize an RPTP with two pseudophosphatase domains, providing evidence that it may act as a decoy receptor for substrate sequestra...

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Autores principales:	Iain M. Hay, Gareth W. Fearnley, Pablo Rios, Maja Köhn, Hayley J. Sharpe, Janet E. Deane
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/43b379ce65a14ab3b79e3d114119ae48
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spelling	oai:doaj.org-article:43b379ce65a14ab3b79e3d114119ae482021-12-02T17:14:28ZThe receptor PTPRU is a redox sensitive pseudophosphatase10.1038/s41467-020-17076-w2041-1723https://doaj.org/article/43b379ce65a14ab3b79e3d114119ae482020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17076-whttps://doaj.org/toc/2041-1723Receptor-linked protein tyrosine phosphatases (RPTPs) usually contain an active membrane proximal domain and an inactive pseudophosphatase domain. Here, the authors characterize an RPTP with two pseudophosphatase domains, providing evidence that it may act as a decoy receptor for substrate sequestration.Iain M. HayGareth W. FearnleyPablo RiosMaja KöhnHayley J. SharpeJanet E. DeaneNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Iain M. Hay Gareth W. Fearnley Pablo Rios Maja Köhn Hayley J. Sharpe Janet E. Deane The receptor PTPRU is a redox sensitive pseudophosphatase
description	Receptor-linked protein tyrosine phosphatases (RPTPs) usually contain an active membrane proximal domain and an inactive pseudophosphatase domain. Here, the authors characterize an RPTP with two pseudophosphatase domains, providing evidence that it may act as a decoy receptor for substrate sequestration.
format	article
author	Iain M. Hay Gareth W. Fearnley Pablo Rios Maja Köhn Hayley J. Sharpe Janet E. Deane
author_facet	Iain M. Hay Gareth W. Fearnley Pablo Rios Maja Köhn Hayley J. Sharpe Janet E. Deane
author_sort	Iain M. Hay
title	The receptor PTPRU is a redox sensitive pseudophosphatase
title_short	The receptor PTPRU is a redox sensitive pseudophosphatase
title_full	The receptor PTPRU is a redox sensitive pseudophosphatase
title_fullStr	The receptor PTPRU is a redox sensitive pseudophosphatase
title_full_unstemmed	The receptor PTPRU is a redox sensitive pseudophosphatase
title_sort	receptor ptpru is a redox sensitive pseudophosphatase
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/43b379ce65a14ab3b79e3d114119ae48
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The receptor PTPRU is a redox sensitive pseudophosphatase

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