Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis

Capsaicin prevents atherosclerotic plaque formation by activating TRPV1 cation channels, but its toxicity precludes its use in clinical settings. Here, Tang and colleagues use copper sulfide nanoparticles as a photothermal switch to locally and temporally activate TRPV1 in vascular smooth muscle cel...

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Autores principales:	Wen Gao, Yuhui Sun, Michelle Cai, Yujie Zhao, Wenhua Cao, Zhenhua Liu, Guanwei Cui, Bo Tang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/43b52c89cc954f199fe0288e8cf87863
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spelling	oai:doaj.org-article:43b52c89cc954f199fe0288e8cf878632021-12-02T15:33:42ZCopper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis10.1038/s41467-017-02657-z2041-1723https://doaj.org/article/43b52c89cc954f199fe0288e8cf878632018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02657-zhttps://doaj.org/toc/2041-1723Capsaicin prevents atherosclerotic plaque formation by activating TRPV1 cation channels, but its toxicity precludes its use in clinical settings. Here, Tang and colleagues use copper sulfide nanoparticles as a photothermal switch to locally and temporally activate TRPV1 in vascular smooth muscle cells and reduce plaque formation without apparent toxicity.Wen GaoYuhui SunMichelle CaiYujie ZhaoWenhua CaoZhenhua LiuGuanwei CuiBo TangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wen Gao Yuhui Sun Michelle Cai Yujie Zhao Wenhua Cao Zhenhua Liu Guanwei Cui Bo Tang Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis
description	Capsaicin prevents atherosclerotic plaque formation by activating TRPV1 cation channels, but its toxicity precludes its use in clinical settings. Here, Tang and colleagues use copper sulfide nanoparticles as a photothermal switch to locally and temporally activate TRPV1 in vascular smooth muscle cells and reduce plaque formation without apparent toxicity.
format	article
author	Wen Gao Yuhui Sun Michelle Cai Yujie Zhao Wenhua Cao Zhenhua Liu Guanwei Cui Bo Tang
author_facet	Wen Gao Yuhui Sun Michelle Cai Yujie Zhao Wenhua Cao Zhenhua Liu Guanwei Cui Bo Tang
author_sort	Wen Gao
title	Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis
title_short	Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis
title_full	Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis
title_fullStr	Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis
title_full_unstemmed	Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis
title_sort	copper sulfide nanoparticles as a photothermal switch for trpv1 signaling to attenuate atherosclerosis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/43b52c89cc954f199fe0288e8cf87863
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Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis

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