Interactions between medical residents and drug companies: a national survey after the Mediator® affair.

<h4>Background</h4>The present study aimed to describe exposure and attitudes of French medical residents towards pharmaceutical industry. The study was performed shortly after the Mediator affair which revealed several serious conflicts of interest inside the French health system.<h4...

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Autores principales: François Montastruc, Guillaume Moulis, Aurore Palmaro, Virginie Gardette, Geneviève Durrieu, Jean-Louis Montastruc
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Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/43cfcdc01bbb49328d523ba890d0282b
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spelling oai:doaj.org-article:43cfcdc01bbb49328d523ba890d0282b2021-11-25T05:57:57ZInteractions between medical residents and drug companies: a national survey after the Mediator® affair.1932-620310.1371/journal.pone.0104828https://doaj.org/article/43cfcdc01bbb49328d523ba890d0282b2014-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0104828https://doaj.org/toc/1932-6203<h4>Background</h4>The present study aimed to describe exposure and attitudes of French medical residents towards pharmaceutical industry. The study was performed shortly after the Mediator affair which revealed several serious conflicts of interest inside the French health system.<h4>Methods and findings</h4>A cross-sectional study was implemented among residents from 6 French medical faculties. Independent education in pharmacology, attitudes towards the practices of pharmaceutical sales representatives, opinions concerning the pharmaceutical industry, quality of information provided by the pharmaceutical industry, and opinions about pharmaceutical company sponsorship were investigated through a web-based questionnaire. We also assessed potential changes in resident attitudes following the Mediator affair. The mean value of exposure to drug companies was 1.9 times per month. Global opinions towards drug company information were negative for 42.7% of the residents and positive for only 8.2%. Surprisingly, 81.6% of residents claimed that they had not changed their practices regarding drug information since the Mediator affair. Multivariate analyses found that residents in anesthesiology were less likely to be exposed than others (OR = 0.17 CI95% [0.05-0.61]), exposure was significantly higher at the beginning of residence (p<0.001) and residents who had a more positive opinion were more frequently exposed to drug companies (OR = 2.12 CI95% [1.07-4.22]).<h4>Conclusions</h4>Resident exposure to drug companies is around 1 contact every 2 weeks. Global opinion towards drug information provided by pharmaceutical companies was negative for around 1 out of 2 residents. In contrast, residents tend to consider the influences of the Mediator affair on their practice as relatively low. This survey enabled us to identify profiles of residents who are obviously less exposed to pharmaceutical industry. Current regulatory provisions are not sufficient, indicating that further efforts are necessary to develop a culture of disclosure of conflict of interest and of transparency in residents.François MontastrucGuillaume MoulisAurore PalmaroVirginie GardetteGeneviève DurrieuJean-Louis MontastrucPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 10, p e104828 (2014)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
François Montastruc
Guillaume Moulis
Aurore Palmaro
Virginie Gardette
Geneviève Durrieu
Jean-Louis Montastruc
Interactions between medical residents and drug companies: a national survey after the Mediator® affair.
description <h4>Background</h4>The present study aimed to describe exposure and attitudes of French medical residents towards pharmaceutical industry. The study was performed shortly after the Mediator affair which revealed several serious conflicts of interest inside the French health system.<h4>Methods and findings</h4>A cross-sectional study was implemented among residents from 6 French medical faculties. Independent education in pharmacology, attitudes towards the practices of pharmaceutical sales representatives, opinions concerning the pharmaceutical industry, quality of information provided by the pharmaceutical industry, and opinions about pharmaceutical company sponsorship were investigated through a web-based questionnaire. We also assessed potential changes in resident attitudes following the Mediator affair. The mean value of exposure to drug companies was 1.9 times per month. Global opinions towards drug company information were negative for 42.7% of the residents and positive for only 8.2%. Surprisingly, 81.6% of residents claimed that they had not changed their practices regarding drug information since the Mediator affair. Multivariate analyses found that residents in anesthesiology were less likely to be exposed than others (OR = 0.17 CI95% [0.05-0.61]), exposure was significantly higher at the beginning of residence (p<0.001) and residents who had a more positive opinion were more frequently exposed to drug companies (OR = 2.12 CI95% [1.07-4.22]).<h4>Conclusions</h4>Resident exposure to drug companies is around 1 contact every 2 weeks. Global opinion towards drug information provided by pharmaceutical companies was negative for around 1 out of 2 residents. In contrast, residents tend to consider the influences of the Mediator affair on their practice as relatively low. This survey enabled us to identify profiles of residents who are obviously less exposed to pharmaceutical industry. Current regulatory provisions are not sufficient, indicating that further efforts are necessary to develop a culture of disclosure of conflict of interest and of transparency in residents.
format article
author François Montastruc
Guillaume Moulis
Aurore Palmaro
Virginie Gardette
Geneviève Durrieu
Jean-Louis Montastruc
author_facet François Montastruc
Guillaume Moulis
Aurore Palmaro
Virginie Gardette
Geneviève Durrieu
Jean-Louis Montastruc
author_sort François Montastruc
title Interactions between medical residents and drug companies: a national survey after the Mediator® affair.
title_short Interactions between medical residents and drug companies: a national survey after the Mediator® affair.
title_full Interactions between medical residents and drug companies: a national survey after the Mediator® affair.
title_fullStr Interactions between medical residents and drug companies: a national survey after the Mediator® affair.
title_full_unstemmed Interactions between medical residents and drug companies: a national survey after the Mediator® affair.
title_sort interactions between medical residents and drug companies: a national survey after the mediator® affair.
publisher Public Library of Science (PLoS)
publishDate 2014
url https://doaj.org/article/43cfcdc01bbb49328d523ba890d0282b
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