The c-Abl inhibitor, radotinib induces apoptosis in multiple myeloma cells via mitochondrial-dependent pathway

Abstract Multiple myeloma (MM) is a hematological cancer resulting from accumulated abnormal plasma cells. Unfortunately, MM remains an incurable disease, as relapse is very common. Therefore, there is urgent need to develop new treatment options for MM. Radotinib is a novel anti-cancer drug, curren...

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Autores principales: Sook-Kyoung Heo, Eui-Kyu Noh, Jeong Yi Kim, Ho-Min Yu, Jun Young Sung, Lan Jeong Ju, Do Kyoung Kim, Hye Jin Seo, Yoo Jin Lee, Jaekyung Cheon, SuJin Koh, Young Joo Min, Yunsuk Choi, Jae-Cheol Jo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/43d427a0131f4e40b71f116b3d316acb
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