In silico analyses of deleterious missense SNPs of human apolipoprotein E3

Abstract ApoE3 is the major chylomicron apolipoprotein, binding in a specific liver peripheral cell receptor, allowing transport and normal catabolism of triglyceride-rich lipoprotein constituents. Point mutations in ApoE3 have been associated with Alzheimer’s disease, type III hyperlipoproteinemia,...

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Bibliographic Details
Main Authors: Allan S. Pires, William F. Porto, Octavio L. Franco, Sérgio A. Alencar
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/43e3c748c0db48c28f20a0cab69056a9
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