In silico analyses of deleterious missense SNPs of human apolipoprotein E3
Abstract ApoE3 is the major chylomicron apolipoprotein, binding in a specific liver peripheral cell receptor, allowing transport and normal catabolism of triglyceride-rich lipoprotein constituents. Point mutations in ApoE3 have been associated with Alzheimer’s disease, type III hyperlipoproteinemia,...
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Main Authors: | Allan S. Pires, William F. Porto, Octavio L. Franco, Sérgio A. Alencar |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/43e3c748c0db48c28f20a0cab69056a9 |
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