MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord

In the spinal cord, someHox genes are transcribed in progenitors while their proteins are only detected in differentiating postmitotic motor neurons. Here, the authors show that miRNAs (specifically mir-27) regulate post-transcriptional Hoxa5 expression in motor neurons.

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Chung-Jung Li, Tian Hong, Ying-Tsen Tung, Ya-Ping Yen, Ho-Chiang Hsu, Ya-Lin Lu, Mien Chang, Qing Nie, Jun-An Chen
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/43eb2d8348ea4cf8b5060a8a551fe66c
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

id	oai:doaj.org-article:43eb2d8348ea4cf8b5060a8a551fe66c
record_format	dspace
spelling	oai:doaj.org-article:43eb2d8348ea4cf8b5060a8a551fe66c2021-12-02T15:38:34ZMicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord10.1038/ncomms146852041-1723https://doaj.org/article/43eb2d8348ea4cf8b5060a8a551fe66c2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14685https://doaj.org/toc/2041-1723In the spinal cord, someHox genes are transcribed in progenitors while their proteins are only detected in differentiating postmitotic motor neurons. Here, the authors show that miRNAs (specifically mir-27) regulate post-transcriptional Hoxa5 expression in motor neurons.Chung-Jung LiTian HongYing-Tsen TungYa-Ping YenHo-Chiang HsuYa-Lin LuMien ChangQing NieJun-An ChenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chung-Jung Li Tian Hong Ying-Tsen Tung Ya-Ping Yen Ho-Chiang Hsu Ya-Lin Lu Mien Chang Qing Nie Jun-An Chen MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
description	In the spinal cord, someHox genes are transcribed in progenitors while their proteins are only detected in differentiating postmitotic motor neurons. Here, the authors show that miRNAs (specifically mir-27) regulate post-transcriptional Hoxa5 expression in motor neurons.
format	article
author	Chung-Jung Li Tian Hong Ying-Tsen Tung Ya-Ping Yen Ho-Chiang Hsu Ya-Lin Lu Mien Chang Qing Nie Jun-An Chen
author_facet	Chung-Jung Li Tian Hong Ying-Tsen Tung Ya-Ping Yen Ho-Chiang Hsu Ya-Lin Lu Mien Chang Qing Nie Jun-An Chen
author_sort	Chung-Jung Li
title	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
title_short	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
title_full	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
title_fullStr	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
title_full_unstemmed	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
title_sort	microrna filters hox temporal transcription noise to confer boundary formation in the spinal cord
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/43eb2d8348ea4cf8b5060a8a551fe66c
work_keys_str_mv	AT chungjungli micrornafiltershoxtemporaltranscriptionnoisetoconferboundaryformationinthespinalcord AT tianhong micrornafiltershoxtemporaltranscriptionnoisetoconferboundaryformationinthespinalcord AT yingtsentung micrornafiltershoxtemporaltranscriptionnoisetoconferboundaryformationinthespinalcord AT yapingyen micrornafiltershoxtemporaltranscriptionnoisetoconferboundaryformationinthespinalcord AT hochianghsu micrornafiltershoxtemporaltranscriptionnoisetoconferboundaryformationinthespinalcord AT yalinlu micrornafiltershoxtemporaltranscriptionnoisetoconferboundaryformationinthespinalcord AT mienchang micrornafiltershoxtemporaltranscriptionnoisetoconferboundaryformationinthespinalcord AT qingnie micrornafiltershoxtemporaltranscriptionnoisetoconferboundaryformationinthespinalcord AT junanchen micrornafiltershoxtemporaltranscriptionnoisetoconferboundaryformationinthespinalcord
_version_	1718386106179780608

MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord

Documents similaires