MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord

In the spinal cord, someHox genes are transcribed in progenitors while their proteins are only detected in differentiating postmitotic motor neurons. Here, the authors show that miRNAs (specifically mir-27) regulate post-transcriptional Hoxa5 expression in motor neurons.

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Autores principales:	Chung-Jung Li, Tian Hong, Ying-Tsen Tung, Ya-Ping Yen, Ho-Chiang Hsu, Ya-Lin Lu, Mien Chang, Qing Nie, Jun-An Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/43eb2d8348ea4cf8b5060a8a551fe66c
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spelling	oai:doaj.org-article:43eb2d8348ea4cf8b5060a8a551fe66c2021-12-02T15:38:34ZMicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord10.1038/ncomms146852041-1723https://doaj.org/article/43eb2d8348ea4cf8b5060a8a551fe66c2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14685https://doaj.org/toc/2041-1723In the spinal cord, someHox genes are transcribed in progenitors while their proteins are only detected in differentiating postmitotic motor neurons. Here, the authors show that miRNAs (specifically mir-27) regulate post-transcriptional Hoxa5 expression in motor neurons.Chung-Jung LiTian HongYing-Tsen TungYa-Ping YenHo-Chiang HsuYa-Lin LuMien ChangQing NieJun-An ChenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chung-Jung Li Tian Hong Ying-Tsen Tung Ya-Ping Yen Ho-Chiang Hsu Ya-Lin Lu Mien Chang Qing Nie Jun-An Chen MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
description	In the spinal cord, someHox genes are transcribed in progenitors while their proteins are only detected in differentiating postmitotic motor neurons. Here, the authors show that miRNAs (specifically mir-27) regulate post-transcriptional Hoxa5 expression in motor neurons.
format	article
author	Chung-Jung Li Tian Hong Ying-Tsen Tung Ya-Ping Yen Ho-Chiang Hsu Ya-Lin Lu Mien Chang Qing Nie Jun-An Chen
author_facet	Chung-Jung Li Tian Hong Ying-Tsen Tung Ya-Ping Yen Ho-Chiang Hsu Ya-Lin Lu Mien Chang Qing Nie Jun-An Chen
author_sort	Chung-Jung Li
title	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
title_short	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
title_full	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
title_fullStr	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
title_full_unstemmed	MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord
title_sort	microrna filters hox temporal transcription noise to confer boundary formation in the spinal cord
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/43eb2d8348ea4cf8b5060a8a551fe66c
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MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord

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