Organic Fluorophores for 1064 nm Excited NIR-II Fluorescence Imaging

Second near-infrared window (NIR-II) fluorescence imaging has shown great potential in the field of bioimaging. However, the excitation wavelengths of most NIR-II fluorescence dyes are in the first near-infrared (NIR-I) region, which leads to limited imaging depth and resolution. To address such iss...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wenqi Wang, Xiaowen He, Mingzhi Du, Chen Xie, Wen Zhou, Wei Huang, Quli Fan
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	NIR-II fluorescence imaging 1,064 nm excitation photothermal therapy phototheranostics organic fluorophores Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/43f513d9babd4d47bf265cd1e6362b1f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:43f513d9babd4d47bf265cd1e6362b1f
record_format	dspace
spelling	oai:doaj.org-article:43f513d9babd4d47bf265cd1e6362b1f2021-11-15T05:48:55ZOrganic Fluorophores for 1064 nm Excited NIR-II Fluorescence Imaging2296-264610.3389/fchem.2021.769655https://doaj.org/article/43f513d9babd4d47bf265cd1e6362b1f2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fchem.2021.769655/fullhttps://doaj.org/toc/2296-2646Second near-infrared window (NIR-II) fluorescence imaging has shown great potential in the field of bioimaging. However, the excitation wavelengths of most NIR-II fluorescence dyes are in the first near-infrared (NIR-I) region, which leads to limited imaging depth and resolution. To address such issue, NIR-II fluorescence dyes with 1,064 nm excitation have been developed and applied for in vivo imaging. Compared with NIR-I wavelength excited dyes, 1,064 nm excited dyes exhibit a higher tissue penetration depth and resolution. The improved performance makes these dyes have much broader imaging applications. In this mini review, we summarize recent advances in 1,064 nm excited NIR-II fluorescence fluorophores for bioimaging. Two kinds of organic fluorophores, small molecule dye and semiconducting polymer (SP), are reviewed. The general properties of these fluorophores are first introduced. Small molecule dyes with different chemical structures for variety of bioimaging applications are then discussed, followed by the introduction of SPs for NIR-II phototheranostics. Finally, the conclusion and future perspective of this field is given.Wenqi WangXiaowen HeMingzhi DuChen XieWen ZhouWei HuangQuli FanFrontiers Media S.A.articleNIR-II fluorescence imaging1,064 nm excitationphotothermal therapyphototheranosticsorganic fluorophoresChemistryQD1-999ENFrontiers in Chemistry, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	NIR-II fluorescence imaging 1,064 nm excitation photothermal therapy phototheranostics organic fluorophores Chemistry QD1-999
spellingShingle	NIR-II fluorescence imaging 1,064 nm excitation photothermal therapy phototheranostics organic fluorophores Chemistry QD1-999 Wenqi Wang Xiaowen He Mingzhi Du Chen Xie Wen Zhou Wei Huang Quli Fan Organic Fluorophores for 1064 nm Excited NIR-II Fluorescence Imaging
description	Second near-infrared window (NIR-II) fluorescence imaging has shown great potential in the field of bioimaging. However, the excitation wavelengths of most NIR-II fluorescence dyes are in the first near-infrared (NIR-I) region, which leads to limited imaging depth and resolution. To address such issue, NIR-II fluorescence dyes with 1,064 nm excitation have been developed and applied for in vivo imaging. Compared with NIR-I wavelength excited dyes, 1,064 nm excited dyes exhibit a higher tissue penetration depth and resolution. The improved performance makes these dyes have much broader imaging applications. In this mini review, we summarize recent advances in 1,064 nm excited NIR-II fluorescence fluorophores for bioimaging. Two kinds of organic fluorophores, small molecule dye and semiconducting polymer (SP), are reviewed. The general properties of these fluorophores are first introduced. Small molecule dyes with different chemical structures for variety of bioimaging applications are then discussed, followed by the introduction of SPs for NIR-II phototheranostics. Finally, the conclusion and future perspective of this field is given.
format	article
author	Wenqi Wang Xiaowen He Mingzhi Du Chen Xie Wen Zhou Wei Huang Quli Fan
author_facet	Wenqi Wang Xiaowen He Mingzhi Du Chen Xie Wen Zhou Wei Huang Quli Fan
author_sort	Wenqi Wang
title	Organic Fluorophores for 1064 nm Excited NIR-II Fluorescence Imaging
title_short	Organic Fluorophores for 1064 nm Excited NIR-II Fluorescence Imaging
title_full	Organic Fluorophores for 1064 nm Excited NIR-II Fluorescence Imaging
title_fullStr	Organic Fluorophores for 1064 nm Excited NIR-II Fluorescence Imaging
title_full_unstemmed	Organic Fluorophores for 1064 nm Excited NIR-II Fluorescence Imaging
title_sort	organic fluorophores for 1064 nm excited nir-ii fluorescence imaging
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/43f513d9babd4d47bf265cd1e6362b1f
work_keys_str_mv	AT wenqiwang organicfluorophoresfor1064nmexcitedniriifluorescenceimaging AT xiaowenhe organicfluorophoresfor1064nmexcitedniriifluorescenceimaging AT mingzhidu organicfluorophoresfor1064nmexcitedniriifluorescenceimaging AT chenxie organicfluorophoresfor1064nmexcitedniriifluorescenceimaging AT wenzhou organicfluorophoresfor1064nmexcitedniriifluorescenceimaging AT weihuang organicfluorophoresfor1064nmexcitedniriifluorescenceimaging AT qulifan organicfluorophoresfor1064nmexcitedniriifluorescenceimaging
_version_	1718428548730978304

Organic Fluorophores for 1064 nm Excited NIR-II Fluorescence Imaging

Ejemplares similares