Evidence-based nanoscopic and molecular framework for excipient functionality in compressed orally disintegrating tablets.

The work investigates the adhesive/cohesive molecular and physical interactions together with nanoscopic features of commonly used orally disintegrating tablet (ODT) excipients microcrystalline cellulose (MCC) and D-mannitol. This helps to elucidate the underlying physico-chemical and mechanical mec...

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Autores principales: Ali Al-Khattawi, Hamad Alyami, Bill Townsend, Xianghong Ma, Afzal R Mohammed
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/43f815b63c724f55b2d419571b86af99
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