The pressure flow relationship of the internal mammary artery after offpump anastomosis to the left anterior descending coronary artery

Objective: To assess the pressure flow relationship of the internal mammary artery (IMA) in situ, after skeletonisation and after anastomosis to the left anterior descending (LAD) coronary artery, using either halothane, sevoflurane or propofol as an anaesthetic agent. Methods: 15 Pigs were used in...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mark B. Connellan, Stephanus J. Roos, André R. Coetzee, Gawie J. Rossouw
Formato:	article
Lenguaje:	EN
Publicado:	South African Heart Association 2017
Materias:	internal mammary artery coronary artery Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/43fcfa45da1f4991a29679a0d5cb8327
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:43fcfa45da1f4991a29679a0d5cb8327
record_format	dspace
spelling	oai:doaj.org-article:43fcfa45da1f4991a29679a0d5cb83272021-11-22T09:04:49ZThe pressure flow relationship of the internal mammary artery after offpump anastomosis to the left anterior descending coronary artery10.24170/6-4-19741996-67412071-4602https://doaj.org/article/43fcfa45da1f4991a29679a0d5cb83272017-04-01T00:00:00Zhttps://www.journals.ac.za/index.php/SAHJ/article/view/1974https://doaj.org/toc/1996-6741https://doaj.org/toc/2071-4602Objective: To assess the pressure flow relationship of the internal mammary artery (IMA) in situ, after skeletonisation and after anastomosis to the left anterior descending (LAD) coronary artery, using either halothane, sevoflurane or propofol as an anaesthetic agent. Methods: 15 Pigs were used in total, five received halothane, five sevoflurane and five propofol as an anaesthetic agent. The flow in the internal mammary artery in each of the pigs, was measured at various arterial pressures. This was done with the IMA in situ, then after dissecting the artery off the chest wall using the skeletonisation technique and finally after offpump grafting to the left anterior descending coronary artery. Results: The pressure flow relationship of the internal mammary artery after skeletonisation was found to be linear (r=0.8650). The pressure flow correlation after grafting the skeletonised internal mammary artery to the left anterior descending coronary artery was found to be similarly linear (r=0.8766). In the sevoflurane subgroup, with the IMA still in situ, a degree of autoregulation was found to be present, but after skeletonisation this was subsequently lost (p=0.011). Conclusions: The pressure flow relationship in the internal mammary artery after skeletonising the vessel and after OPCAB anastomosis to the LAD was found to be linear. In the subgroup of pigs receiving sevoflurane, some degree of autoregulation was demonstrated in the in situ IMA. This remnant of autoregulation was lost after skeletonisation and after grafting of the vessel to the left anterior descending coronary artery.Mark B. ConnellanStephanus J. RoosAndré R. CoetzeeGawie J. RossouwSouth African Heart Associationarticleinternal mammary arterycoronary arteryDiseases of the circulatory (Cardiovascular) systemRC666-701ENSA Heart Journal, Vol 6, Iss 4, Pp 222-228 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	internal mammary artery coronary artery Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	internal mammary artery coronary artery Diseases of the circulatory (Cardiovascular) system RC666-701 Mark B. Connellan Stephanus J. Roos André R. Coetzee Gawie J. Rossouw The pressure flow relationship of the internal mammary artery after offpump anastomosis to the left anterior descending coronary artery
description	Objective: To assess the pressure flow relationship of the internal mammary artery (IMA) in situ, after skeletonisation and after anastomosis to the left anterior descending (LAD) coronary artery, using either halothane, sevoflurane or propofol as an anaesthetic agent. Methods: 15 Pigs were used in total, five received halothane, five sevoflurane and five propofol as an anaesthetic agent. The flow in the internal mammary artery in each of the pigs, was measured at various arterial pressures. This was done with the IMA in situ, then after dissecting the artery off the chest wall using the skeletonisation technique and finally after offpump grafting to the left anterior descending coronary artery. Results: The pressure flow relationship of the internal mammary artery after skeletonisation was found to be linear (r=0.8650). The pressure flow correlation after grafting the skeletonised internal mammary artery to the left anterior descending coronary artery was found to be similarly linear (r=0.8766). In the sevoflurane subgroup, with the IMA still in situ, a degree of autoregulation was found to be present, but after skeletonisation this was subsequently lost (p=0.011). Conclusions: The pressure flow relationship in the internal mammary artery after skeletonising the vessel and after OPCAB anastomosis to the LAD was found to be linear. In the subgroup of pigs receiving sevoflurane, some degree of autoregulation was demonstrated in the in situ IMA. This remnant of autoregulation was lost after skeletonisation and after grafting of the vessel to the left anterior descending coronary artery.
format	article
author	Mark B. Connellan Stephanus J. Roos André R. Coetzee Gawie J. Rossouw
author_facet	Mark B. Connellan Stephanus J. Roos André R. Coetzee Gawie J. Rossouw
author_sort	Mark B. Connellan
title	The pressure flow relationship of the internal mammary artery after offpump anastomosis to the left anterior descending coronary artery
title_short	The pressure flow relationship of the internal mammary artery after offpump anastomosis to the left anterior descending coronary artery
title_full	The pressure flow relationship of the internal mammary artery after offpump anastomosis to the left anterior descending coronary artery
title_fullStr	The pressure flow relationship of the internal mammary artery after offpump anastomosis to the left anterior descending coronary artery
title_full_unstemmed	The pressure flow relationship of the internal mammary artery after offpump anastomosis to the left anterior descending coronary artery
title_sort	pressure flow relationship of the internal mammary artery after offpump anastomosis to the left anterior descending coronary artery
publisher	South African Heart Association
publishDate	2017
url	https://doaj.org/article/43fcfa45da1f4991a29679a0d5cb8327
work_keys_str_mv	AT markbconnellan thepressureflowrelationshipoftheinternalmammaryarteryafteroffpumpanastomosistotheleftanteriordescendingcoronaryartery AT stephanusjroos thepressureflowrelationshipoftheinternalmammaryarteryafteroffpumpanastomosistotheleftanteriordescendingcoronaryartery AT andrercoetzee thepressureflowrelationshipoftheinternalmammaryarteryafteroffpumpanastomosistotheleftanteriordescendingcoronaryartery AT gawiejrossouw thepressureflowrelationshipoftheinternalmammaryarteryafteroffpumpanastomosistotheleftanteriordescendingcoronaryartery AT markbconnellan pressureflowrelationshipoftheinternalmammaryarteryafteroffpumpanastomosistotheleftanteriordescendingcoronaryartery AT stephanusjroos pressureflowrelationshipoftheinternalmammaryarteryafteroffpumpanastomosistotheleftanteriordescendingcoronaryartery AT andrercoetzee pressureflowrelationshipoftheinternalmammaryarteryafteroffpumpanastomosistotheleftanteriordescendingcoronaryartery AT gawiejrossouw pressureflowrelationshipoftheinternalmammaryarteryafteroffpumpanastomosistotheleftanteriordescendingcoronaryartery
_version_	1718417790350655488

The pressure flow relationship of the internal mammary artery after offpump anastomosis to the left anterior descending coronary artery

Ejemplares similares