Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™.

Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™.

Xeroderma pigmentosum group C (XP-C) is a rare human syndrome characterized by hypersensitivity to UV light and a dramatic predisposition to skin neoplasms. XP-C cells are deficient in the nucleotide excision repair (NER) pathway, a complex process involved in the recognition and removal of DNA lesi...

Full description

Saved in:
Bibliographic Details
Main Authors: Aurélie Dupuy, Julien Valton, Sophie Leduc, Jacques Armier, Roman Galetto, Agnès Gouble, Céline Lebuhotel, Anne Stary, Frédéric Pâques, Philippe Duchateau, Alain Sarasin, Fayza Daboussi
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/43fe12d192c34e43908b529a3573f188
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/43fe12d192c34e43908b529a3573f188

Similar Items