Profiling surface proteins on individual exosomes using a proximity barcoding assay

Profiling surface proteins on individual exosomes using a proximity barcoding assay

The use of antibodies to capture and profile exosomes limits the number of target proteins that can be detected. Here the authors develop a proximity-dependent barcoding assay that allows profiling of 38 surface proteins on individual exosomes from heterogeneous samples such as serum and seminal flu...

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Autores principales: Di Wu, Junhong Yan, Xia Shen, Yu Sun, Måns Thulin, Yanling Cai, Lotta Wik, Qiujin Shen, Johan Oelrich, Xiaoyan Qian, K. Louise Dubois, K. Göran Ronquist, Mats Nilsson, Ulf Landegren, Masood Kamali-Moghaddam
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Q
Acceso en línea:https://doaj.org/article/4401bffea1974cedb4e3e3e029718359
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spelling oai:doaj.org-article:4401bffea1974cedb4e3e3e0297183592021-12-02T14:40:20ZProfiling surface proteins on individual exosomes using a proximity barcoding assay10.1038/s41467-019-11486-12041-1723https://doaj.org/article/4401bffea1974cedb4e3e3e0297183592019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11486-1https://doaj.org/toc/2041-1723The use of antibodies to capture and profile exosomes limits the number of target proteins that can be detected. Here the authors develop a proximity-dependent barcoding assay that allows profiling of 38 surface proteins on individual exosomes from heterogeneous samples such as serum and seminal fluid.Di WuJunhong YanXia ShenYu SunMåns ThulinYanling CaiLotta WikQiujin ShenJohan OelrichXiaoyan QianK. Louise DuboisK. Göran RonquistMats NilssonUlf LandegrenMasood Kamali-MoghaddamNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Di Wu
Junhong Yan
Xia Shen
Yu Sun
Måns Thulin
Yanling Cai
Lotta Wik
Qiujin Shen
Johan Oelrich
Xiaoyan Qian
K. Louise Dubois
K. Göran Ronquist
Mats Nilsson
Ulf Landegren
Masood Kamali-Moghaddam
Profiling surface proteins on individual exosomes using a proximity barcoding assay
description The use of antibodies to capture and profile exosomes limits the number of target proteins that can be detected. Here the authors develop a proximity-dependent barcoding assay that allows profiling of 38 surface proteins on individual exosomes from heterogeneous samples such as serum and seminal fluid.
format article
author Di Wu
Junhong Yan
Xia Shen
Yu Sun
Måns Thulin
Yanling Cai
Lotta Wik
Qiujin Shen
Johan Oelrich
Xiaoyan Qian
K. Louise Dubois
K. Göran Ronquist
Mats Nilsson
Ulf Landegren
Masood Kamali-Moghaddam
author_facet Di Wu
Junhong Yan
Xia Shen
Yu Sun
Måns Thulin
Yanling Cai
Lotta Wik
Qiujin Shen
Johan Oelrich
Xiaoyan Qian
K. Louise Dubois
K. Göran Ronquist
Mats Nilsson
Ulf Landegren
Masood Kamali-Moghaddam
author_sort Di Wu
title Profiling surface proteins on individual exosomes using a proximity barcoding assay
title_short Profiling surface proteins on individual exosomes using a proximity barcoding assay
title_full Profiling surface proteins on individual exosomes using a proximity barcoding assay
title_fullStr Profiling surface proteins on individual exosomes using a proximity barcoding assay
title_full_unstemmed Profiling surface proteins on individual exosomes using a proximity barcoding assay
title_sort profiling surface proteins on individual exosomes using a proximity barcoding assay
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/4401bffea1974cedb4e3e3e029718359
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AT xiashen profilingsurfaceproteinsonindividualexosomesusingaproximitybarcodingassay
AT yusun profilingsurfaceproteinsonindividualexosomesusingaproximitybarcodingassay
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