Precardiac organoids form two heart fields via Bmp/Wnt signaling

The heart arises from distinct progenitor cells of both the first and second heart fields (FHF and SHF). Here, the authors generated precardiac organoids from mouse and human pluripotent cells and show that FHF and SHF cells form similarly to their in vivo counterparts in response to BMP and Wnt sig...

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Autores principales:	Peter Andersen, Emmanouil Tampakakis, Dennisse V. Jimenez, Suraj Kannan, Matthew Miyamoto, Hye Kyung Shin, Amir Saberi, Sean Murphy, Edrick Sulistio, Stephen P. Chelko, Chulan Kwon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4409cf8489414ab6a468a5e03fc7c274
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spelling	oai:doaj.org-article:4409cf8489414ab6a468a5e03fc7c2742021-12-02T17:31:11ZPrecardiac organoids form two heart fields via Bmp/Wnt signaling10.1038/s41467-018-05604-82041-1723https://doaj.org/article/4409cf8489414ab6a468a5e03fc7c2742018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05604-8https://doaj.org/toc/2041-1723The heart arises from distinct progenitor cells of both the first and second heart fields (FHF and SHF). Here, the authors generated precardiac organoids from mouse and human pluripotent cells and show that FHF and SHF cells form similarly to their in vivo counterparts in response to BMP and Wnt signalling, respectively.Peter AndersenEmmanouil TampakakisDennisse V. JimenezSuraj KannanMatthew MiyamotoHye Kyung ShinAmir SaberiSean MurphyEdrick SulistioStephen P. ChelkoChulan KwonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Peter Andersen Emmanouil Tampakakis Dennisse V. Jimenez Suraj Kannan Matthew Miyamoto Hye Kyung Shin Amir Saberi Sean Murphy Edrick Sulistio Stephen P. Chelko Chulan Kwon Precardiac organoids form two heart fields via Bmp/Wnt signaling
description	The heart arises from distinct progenitor cells of both the first and second heart fields (FHF and SHF). Here, the authors generated precardiac organoids from mouse and human pluripotent cells and show that FHF and SHF cells form similarly to their in vivo counterparts in response to BMP and Wnt signalling, respectively.
format	article
author	Peter Andersen Emmanouil Tampakakis Dennisse V. Jimenez Suraj Kannan Matthew Miyamoto Hye Kyung Shin Amir Saberi Sean Murphy Edrick Sulistio Stephen P. Chelko Chulan Kwon
author_facet	Peter Andersen Emmanouil Tampakakis Dennisse V. Jimenez Suraj Kannan Matthew Miyamoto Hye Kyung Shin Amir Saberi Sean Murphy Edrick Sulistio Stephen P. Chelko Chulan Kwon
author_sort	Peter Andersen
title	Precardiac organoids form two heart fields via Bmp/Wnt signaling
title_short	Precardiac organoids form two heart fields via Bmp/Wnt signaling
title_full	Precardiac organoids form two heart fields via Bmp/Wnt signaling
title_fullStr	Precardiac organoids form two heart fields via Bmp/Wnt signaling
title_full_unstemmed	Precardiac organoids form two heart fields via Bmp/Wnt signaling
title_sort	precardiac organoids form two heart fields via bmp/wnt signaling
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/4409cf8489414ab6a468a5e03fc7c274
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Precardiac organoids form two heart fields via Bmp/Wnt signaling

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