Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis

Progressive fibrosis is a driver of morbidity and mortality in many chronic liver diseases, but the underlying mechanisms are incompletely understood. Here, the authors show that mitochondria-derived damage-associated molecular patterns are released from injured hepatocytes and can trigger fibrogeni...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ping An, Lin-Lin Wei, Shuangshuang Zhao, Deanna Y. Sverdlov, Kahini A. Vaid, Makoto Miyamoto, Kaori Kuramitsu, Michelle Lai, Yury V. Popov
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/44134943fce4419c97cee7871e6d7d2d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares