Clozapine prescribing in a Canadian outpatient population.

<h4>Objective</h4>Description of demographics of an outpatient population of clozapine users.<h4>Methods</h4>Retrospective chart review study of an urban population diagnosed with schizophrenia. Assessment of therapeutic histories in relation to clinical practice guidelines.&...

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Autores principales:	Silvia Alessi-Severini, Josee-Anne Le Dorze, David Nguyen, Patricia Honcharik, Michael Eleff
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/441483027ff44d28acbd42487ae0f184
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spelling	oai:doaj.org-article:441483027ff44d28acbd42487ae0f1842021-11-18T08:41:43ZClozapine prescribing in a Canadian outpatient population.1932-620310.1371/journal.pone.0083539https://doaj.org/article/441483027ff44d28acbd42487ae0f1842013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24358290/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objective</h4>Description of demographics of an outpatient population of clozapine users.<h4>Methods</h4>Retrospective chart review study of an urban population diagnosed with schizophrenia. Assessment of therapeutic histories in relation to clinical practice guidelines.<h4>Results</h4>Seventy-seven of the 467 patients were on clozapine therapy. Average patients' age was 39.4 ± 11.8 years) and 68% were males. The majority of patients (68%) had tried 3 or more antipsychotics before switching to clozapine, 21% had tried two and 11% had tried one. Median length of therapy prior to clozapine initiation was 8.9 years in males and 7.7 years in females.<h4>Conclusion</h4>Until 2010, the use of clozapine was often delayed and more than 2 antipsychotic medications were tried for relatively long periods of time before patients were switched to this effective agent.Silvia Alessi-SeveriniJosee-Anne Le DorzeDavid NguyenPatricia HoncharikMichael EleffPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 12, p e83539 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Silvia Alessi-Severini Josee-Anne Le Dorze David Nguyen Patricia Honcharik Michael Eleff Clozapine prescribing in a Canadian outpatient population.
description	<h4>Objective</h4>Description of demographics of an outpatient population of clozapine users.<h4>Methods</h4>Retrospective chart review study of an urban population diagnosed with schizophrenia. Assessment of therapeutic histories in relation to clinical practice guidelines.<h4>Results</h4>Seventy-seven of the 467 patients were on clozapine therapy. Average patients' age was 39.4 ± 11.8 years) and 68% were males. The majority of patients (68%) had tried 3 or more antipsychotics before switching to clozapine, 21% had tried two and 11% had tried one. Median length of therapy prior to clozapine initiation was 8.9 years in males and 7.7 years in females.<h4>Conclusion</h4>Until 2010, the use of clozapine was often delayed and more than 2 antipsychotic medications were tried for relatively long periods of time before patients were switched to this effective agent.
format	article
author	Silvia Alessi-Severini Josee-Anne Le Dorze David Nguyen Patricia Honcharik Michael Eleff
author_facet	Silvia Alessi-Severini Josee-Anne Le Dorze David Nguyen Patricia Honcharik Michael Eleff
author_sort	Silvia Alessi-Severini
title	Clozapine prescribing in a Canadian outpatient population.
title_short	Clozapine prescribing in a Canadian outpatient population.
title_full	Clozapine prescribing in a Canadian outpatient population.
title_fullStr	Clozapine prescribing in a Canadian outpatient population.
title_full_unstemmed	Clozapine prescribing in a Canadian outpatient population.
title_sort	clozapine prescribing in a canadian outpatient population.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/441483027ff44d28acbd42487ae0f184
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Clozapine prescribing in a Canadian outpatient population.

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