Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures

The correlation between brain structural changes in major depressive disorder (MDD) and gene expression is unclear. Here, the authors explore the correlation between cell type-specific gene expression changes and cortical structural difference in individuals with major depressive disorder.

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Detalles Bibliográficos
Autores principales: Jiao Li, Jakob Seidlitz, John Suckling, Feiyang Fan, Gong-Jun Ji, Yao Meng, Siqi Yang, Kai Wang, Jiang Qiu, Huafu Chen, Wei Liao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4419cffc0bad4a63855862546d424e59
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Sumario:The correlation between brain structural changes in major depressive disorder (MDD) and gene expression is unclear. Here, the authors explore the correlation between cell type-specific gene expression changes and cortical structural difference in individuals with major depressive disorder.