Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures

The correlation between brain structural changes in major depressive disorder (MDD) and gene expression is unclear. Here, the authors explore the correlation between cell type-specific gene expression changes and cortical structural difference in individuals with major depressive disorder.

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Autores principales:	Jiao Li, Jakob Seidlitz, John Suckling, Feiyang Fan, Gong-Jun Ji, Yao Meng, Siqi Yang, Kai Wang, Jiang Qiu, Huafu Chen, Wei Liao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4419cffc0bad4a63855862546d424e59
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spelling	oai:doaj.org-article:4419cffc0bad4a63855862546d424e592021-12-02T15:52:28ZCortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures10.1038/s41467-021-21943-52041-1723https://doaj.org/article/4419cffc0bad4a63855862546d424e592021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21943-5https://doaj.org/toc/2041-1723The correlation between brain structural changes in major depressive disorder (MDD) and gene expression is unclear. Here, the authors explore the correlation between cell type-specific gene expression changes and cortical structural difference in individuals with major depressive disorder.Jiao LiJakob SeidlitzJohn SucklingFeiyang FanGong-Jun JiYao MengSiqi YangKai WangJiang QiuHuafu ChenWei LiaoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiao Li Jakob Seidlitz John Suckling Feiyang Fan Gong-Jun Ji Yao Meng Siqi Yang Kai Wang Jiang Qiu Huafu Chen Wei Liao Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
description	The correlation between brain structural changes in major depressive disorder (MDD) and gene expression is unclear. Here, the authors explore the correlation between cell type-specific gene expression changes and cortical structural difference in individuals with major depressive disorder.
format	article
author	Jiao Li Jakob Seidlitz John Suckling Feiyang Fan Gong-Jun Ji Yao Meng Siqi Yang Kai Wang Jiang Qiu Huafu Chen Wei Liao
author_facet	Jiao Li Jakob Seidlitz John Suckling Feiyang Fan Gong-Jun Ji Yao Meng Siqi Yang Kai Wang Jiang Qiu Huafu Chen Wei Liao
author_sort	Jiao Li
title	Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
title_short	Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
title_full	Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
title_fullStr	Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
title_full_unstemmed	Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
title_sort	cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4419cffc0bad4a63855862546d424e59
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Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures

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