Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease?

Mixed connective tissue disease (MCTD) is a complex entity, which incorporates features of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc) and polymyositis/dermatomyositis (PM/DM). Nailfold videocapillaroscopy (NVC) is a simple, safe and non-invasive technique...

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Autores principales: Sylwia Ornowska, Marek Chojnowski, Anna Felis-Giemza, Łukasz Dudek, Marzena Olesińska
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Lenguaje:EN
Publicado: Termedia Publishing House 2021
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Acceso en línea:https://doaj.org/article/44288467ae4843d5bfd4ec60865cf45c
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spelling oai:doaj.org-article:44288467ae4843d5bfd4ec60865cf45c2021-12-02T18:55:18ZMicrovascular damage – a marker of specific organ involvement in mixed connective tissue disease?0034-62332084-983410.5114/reum.2021.105457https://doaj.org/article/44288467ae4843d5bfd4ec60865cf45c2021-04-01T00:00:00Zhttps://www.termedia.pl/Microvascular-damage-a-marker-of-specific-organ-involvement-in-mixed-connective-tissue-disease-,18,43879,1,1.htmlhttps://doaj.org/toc/0034-6233https://doaj.org/toc/2084-9834Mixed connective tissue disease (MCTD) is a complex entity, which incorporates features of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc) and polymyositis/dermatomyositis (PM/DM). Nailfold videocapillaroscopy (NVC) is a simple, safe and non-invasive technique of capillary vessel assessment, allowing for qualitative and quantitative assessment of microcirculation. NVC plays a pivotal role in the diagnostic algorithm of connective tissue diseases, especially in systemic sclerosis (SSc). Numerous studies have shown a correlation between organ involvement and disease progression in SSc. In the current literature, there are limited data on relationship between NVC and organ involvement in MCTD patients. In the present article the relevant literature describing NVC examination in patients with MCTD and comparisons with some clinical situations are discussed.Sylwia OrnowskaMarek ChojnowskiAnna Felis-GiemzaŁukasz DudekMarzena OlesińskaTermedia Publishing Housearticlesystemic sclerosis connective tissue disease microscopy microvascular damage.MedicineRENRheumatology, Vol 59, Iss 2, Pp 115-120 (2021)
institution DOAJ
collection DOAJ
language EN
topic systemic sclerosis
connective tissue disease
microscopy
microvascular damage.
Medicine
R
spellingShingle systemic sclerosis
connective tissue disease
microscopy
microvascular damage.
Medicine
R
Sylwia Ornowska
Marek Chojnowski
Anna Felis-Giemza
Łukasz Dudek
Marzena Olesińska
Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease?
description Mixed connective tissue disease (MCTD) is a complex entity, which incorporates features of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc) and polymyositis/dermatomyositis (PM/DM). Nailfold videocapillaroscopy (NVC) is a simple, safe and non-invasive technique of capillary vessel assessment, allowing for qualitative and quantitative assessment of microcirculation. NVC plays a pivotal role in the diagnostic algorithm of connective tissue diseases, especially in systemic sclerosis (SSc). Numerous studies have shown a correlation between organ involvement and disease progression in SSc. In the current literature, there are limited data on relationship between NVC and organ involvement in MCTD patients. In the present article the relevant literature describing NVC examination in patients with MCTD and comparisons with some clinical situations are discussed.
format article
author Sylwia Ornowska
Marek Chojnowski
Anna Felis-Giemza
Łukasz Dudek
Marzena Olesińska
author_facet Sylwia Ornowska
Marek Chojnowski
Anna Felis-Giemza
Łukasz Dudek
Marzena Olesińska
author_sort Sylwia Ornowska
title Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease?
title_short Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease?
title_full Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease?
title_fullStr Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease?
title_full_unstemmed Microvascular damage – a marker of specific organ involvement in mixed connective tissue disease?
title_sort microvascular damage – a marker of specific organ involvement in mixed connective tissue disease?
publisher Termedia Publishing House
publishDate 2021
url https://doaj.org/article/44288467ae4843d5bfd4ec60865cf45c
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AT łukaszdudek microvasculardamageamarkerofspecificorganinvolvementinmixedconnectivetissuedisease
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