mSphere of Influence: Combining Host and Pathogen Genetics To Disrupt Chronic Infections

ABSTRACT Andrew J. Olive works in the field of host responses to chronic infections. In this mSphere of Influence article, he reflects on how “Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing” (Y. J. Zhang, M. C. Reddy, T. R. Ioerger, A. C. Rothchild, et al., Cell 155:1...

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Autor principal: Andrew J. Olive
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/442aca41a1e34a45aa79801956426af5
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spelling oai:doaj.org-article:442aca41a1e34a45aa79801956426af52021-11-15T15:27:54ZmSphere of Influence: Combining Host and Pathogen Genetics To Disrupt Chronic Infections10.1128/mSphere.00106-202379-5042https://doaj.org/article/442aca41a1e34a45aa79801956426af52020-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00106-20https://doaj.org/toc/2379-5042ABSTRACT Andrew J. Olive works in the field of host responses to chronic infections. In this mSphere of Influence article, he reflects on how “Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing” (Y. J. Zhang, M. C. Reddy, T. R. Ioerger, A. C. Rothchild, et al., Cell 155:1296–1308, 2013, https://doi.org/10.1016/j.cell.2013.10.045) impacted his own work using genetic approaches to dissect the interface between host and pathogen.Andrew J. OliveAmerican Society for MicrobiologyarticleMycobacteriumMycobacterium tuberculosisgeneticsimmune evasionpersistent infectionstransposon sequencingMicrobiologyQR1-502ENmSphere, Vol 5, Iss 1 (2020)
institution DOAJ
collection DOAJ
language EN
topic Mycobacterium
Mycobacterium tuberculosis
genetics
immune evasion
persistent infections
transposon sequencing
Microbiology
QR1-502
spellingShingle Mycobacterium
Mycobacterium tuberculosis
genetics
immune evasion
persistent infections
transposon sequencing
Microbiology
QR1-502
Andrew J. Olive
mSphere of Influence: Combining Host and Pathogen Genetics To Disrupt Chronic Infections
description ABSTRACT Andrew J. Olive works in the field of host responses to chronic infections. In this mSphere of Influence article, he reflects on how “Tryptophan biosynthesis protects mycobacteria from CD4 T-cell-mediated killing” (Y. J. Zhang, M. C. Reddy, T. R. Ioerger, A. C. Rothchild, et al., Cell 155:1296–1308, 2013, https://doi.org/10.1016/j.cell.2013.10.045) impacted his own work using genetic approaches to dissect the interface between host and pathogen.
format article
author Andrew J. Olive
author_facet Andrew J. Olive
author_sort Andrew J. Olive
title mSphere of Influence: Combining Host and Pathogen Genetics To Disrupt Chronic Infections
title_short mSphere of Influence: Combining Host and Pathogen Genetics To Disrupt Chronic Infections
title_full mSphere of Influence: Combining Host and Pathogen Genetics To Disrupt Chronic Infections
title_fullStr mSphere of Influence: Combining Host and Pathogen Genetics To Disrupt Chronic Infections
title_full_unstemmed mSphere of Influence: Combining Host and Pathogen Genetics To Disrupt Chronic Infections
title_sort msphere of influence: combining host and pathogen genetics to disrupt chronic infections
publisher American Society for Microbiology
publishDate 2020
url https://doaj.org/article/442aca41a1e34a45aa79801956426af5
work_keys_str_mv AT andrewjolive msphereofinfluencecombininghostandpathogengeneticstodisruptchronicinfections
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