Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells

Pericytes and vascular smooth muscle cells are crucial for functional blood vessels, but the developmental sources of these cells are incompletely understood. Here, the authors show that endocardial endothelial cells give rise to cardiac mural cells, which are controlled by Wnt signalling.

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Autores principales:	Qi Chen, Hui Zhang, Yang Liu, Susanne Adams, Hanna Eilken, Martin Stehling, Monica Corada, Elisabetta Dejana, Bin Zhou, Ralf H. Adams
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/442c956f54bf4c6eba0ef2653c390245
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spelling	oai:doaj.org-article:442c956f54bf4c6eba0ef2653c3902452021-12-02T17:31:18ZEndothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells10.1038/ncomms124222041-1723https://doaj.org/article/442c956f54bf4c6eba0ef2653c3902452016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12422https://doaj.org/toc/2041-1723Pericytes and vascular smooth muscle cells are crucial for functional blood vessels, but the developmental sources of these cells are incompletely understood. Here, the authors show that endocardial endothelial cells give rise to cardiac mural cells, which are controlled by Wnt signalling.Qi ChenHui ZhangYang LiuSusanne AdamsHanna EilkenMartin StehlingMonica CoradaElisabetta DejanaBin ZhouRalf H. AdamsNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qi Chen Hui Zhang Yang Liu Susanne Adams Hanna Eilken Martin Stehling Monica Corada Elisabetta Dejana Bin Zhou Ralf H. Adams Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells
description	Pericytes and vascular smooth muscle cells are crucial for functional blood vessels, but the developmental sources of these cells are incompletely understood. Here, the authors show that endocardial endothelial cells give rise to cardiac mural cells, which are controlled by Wnt signalling.
format	article
author	Qi Chen Hui Zhang Yang Liu Susanne Adams Hanna Eilken Martin Stehling Monica Corada Elisabetta Dejana Bin Zhou Ralf H. Adams
author_facet	Qi Chen Hui Zhang Yang Liu Susanne Adams Hanna Eilken Martin Stehling Monica Corada Elisabetta Dejana Bin Zhou Ralf H. Adams
author_sort	Qi Chen
title	Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells
title_short	Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells
title_full	Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells
title_fullStr	Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells
title_full_unstemmed	Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells
title_sort	endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/442c956f54bf4c6eba0ef2653c390245
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Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells

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