The transferability of lipid loci across African, Asian and European cohorts

The majority of published GWAS was performed in European ancestry populations. Here, Kuchenbaecker et al., test to which extent lipid loci are shared and find that the major lipid loci are mostly transferrable between Europeans and Asians while there are notable exceptions for African populations.

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Autores principales:	Karoline Kuchenbaecker, Nikita Telkar, Theresa Reiker, Robin G. Walters, Kuang Lin, Anders Eriksson, Deepti Gurdasani, Arthur Gilly, Lorraine Southam, Emmanouil Tsafantakis, Maria Karaleftheri, Janet Seeley, Anatoli Kamali, Gershim Asiki, Iona Y. Millwood, Michael Holmes, Huaidong Du, Yu Guo, Meena Kumari, George Dedoussis, Liming Li, Zhengming Chen, Manjinder S. Sandhu, Eleftheria Zeggini, Understanding Society Scientific Group
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/442fbc04a95d4e22903a961fed36fb1d
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spelling	oai:doaj.org-article:442fbc04a95d4e22903a961fed36fb1d2021-12-02T16:58:06ZThe transferability of lipid loci across African, Asian and European cohorts10.1038/s41467-019-12026-72041-1723https://doaj.org/article/442fbc04a95d4e22903a961fed36fb1d2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12026-7https://doaj.org/toc/2041-1723The majority of published GWAS was performed in European ancestry populations. Here, Kuchenbaecker et al., test to which extent lipid loci are shared and find that the major lipid loci are mostly transferrable between Europeans and Asians while there are notable exceptions for African populations.Karoline KuchenbaeckerNikita TelkarTheresa ReikerRobin G. WaltersKuang LinAnders ErikssonDeepti GurdasaniArthur GillyLorraine SouthamEmmanouil TsafantakisMaria KaraleftheriJanet SeeleyAnatoli KamaliGershim AsikiIona Y. MillwoodMichael HolmesHuaidong DuYu GuoMeena KumariGeorge DedoussisLiming LiZhengming ChenManjinder S. SandhuEleftheria ZegginiUnderstanding Society Scientific GroupNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Karoline Kuchenbaecker Nikita Telkar Theresa Reiker Robin G. Walters Kuang Lin Anders Eriksson Deepti Gurdasani Arthur Gilly Lorraine Southam Emmanouil Tsafantakis Maria Karaleftheri Janet Seeley Anatoli Kamali Gershim Asiki Iona Y. Millwood Michael Holmes Huaidong Du Yu Guo Meena Kumari George Dedoussis Liming Li Zhengming Chen Manjinder S. Sandhu Eleftheria Zeggini Understanding Society Scientific Group The transferability of lipid loci across African, Asian and European cohorts
description	The majority of published GWAS was performed in European ancestry populations. Here, Kuchenbaecker et al., test to which extent lipid loci are shared and find that the major lipid loci are mostly transferrable between Europeans and Asians while there are notable exceptions for African populations.
format	article
author	Karoline Kuchenbaecker Nikita Telkar Theresa Reiker Robin G. Walters Kuang Lin Anders Eriksson Deepti Gurdasani Arthur Gilly Lorraine Southam Emmanouil Tsafantakis Maria Karaleftheri Janet Seeley Anatoli Kamali Gershim Asiki Iona Y. Millwood Michael Holmes Huaidong Du Yu Guo Meena Kumari George Dedoussis Liming Li Zhengming Chen Manjinder S. Sandhu Eleftheria Zeggini Understanding Society Scientific Group
author_facet	Karoline Kuchenbaecker Nikita Telkar Theresa Reiker Robin G. Walters Kuang Lin Anders Eriksson Deepti Gurdasani Arthur Gilly Lorraine Southam Emmanouil Tsafantakis Maria Karaleftheri Janet Seeley Anatoli Kamali Gershim Asiki Iona Y. Millwood Michael Holmes Huaidong Du Yu Guo Meena Kumari George Dedoussis Liming Li Zhengming Chen Manjinder S. Sandhu Eleftheria Zeggini Understanding Society Scientific Group
author_sort	Karoline Kuchenbaecker
title	The transferability of lipid loci across African, Asian and European cohorts
title_short	The transferability of lipid loci across African, Asian and European cohorts
title_full	The transferability of lipid loci across African, Asian and European cohorts
title_fullStr	The transferability of lipid loci across African, Asian and European cohorts
title_full_unstemmed	The transferability of lipid loci across African, Asian and European cohorts
title_sort	transferability of lipid loci across african, asian and european cohorts
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/442fbc04a95d4e22903a961fed36fb1d
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The transferability of lipid loci across African, Asian and European cohorts

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