Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade

The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface.

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Detalles Bibliográficos
Autores principales: Yifei Zhang, Stanislav Tsitkov, Henry Hess
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Q
Acceso en línea:https://doaj.org/article/44331a73a8a447e48a8689599bc13ffd
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Sumario:The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface.