Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade

The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface.

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Détails bibliographiques
Auteurs principaux:	Yifei Zhang, Stanislav Tsitkov, Henry Hess
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2016
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/44331a73a8a447e48a8689599bc13ffd
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spelling	oai:doaj.org-article:44331a73a8a447e48a8689599bc13ffd2021-12-02T17:31:34ZProximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade10.1038/ncomms139822041-1723https://doaj.org/article/44331a73a8a447e48a8689599bc13ffd2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13982https://doaj.org/toc/2041-1723The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface.Yifei ZhangStanislav TsitkovHenry HessNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yifei Zhang Stanislav Tsitkov Henry Hess Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
description	The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface.
format	article
author	Yifei Zhang Stanislav Tsitkov Henry Hess
author_facet	Yifei Zhang Stanislav Tsitkov Henry Hess
author_sort	Yifei Zhang
title	Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
title_short	Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
title_full	Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
title_fullStr	Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
title_full_unstemmed	Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
title_sort	proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/44331a73a8a447e48a8689599bc13ffd
work_keys_str_mv	AT yifeizhang proximitydoesnotcontributetoactivityenhancementintheglucoseoxidasehorseradishperoxidasecascade AT stanislavtsitkov proximitydoesnotcontributetoactivityenhancementintheglucoseoxidasehorseradishperoxidasecascade AT henryhess proximitydoesnotcontributetoactivityenhancementintheglucoseoxidasehorseradishperoxidasecascade
_version_	1718380548438622208

Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade

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