Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade

The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface.

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Autores principales: Yifei Zhang, Stanislav Tsitkov, Henry Hess
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/44331a73a8a447e48a8689599bc13ffd
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spelling oai:doaj.org-article:44331a73a8a447e48a8689599bc13ffd2021-12-02T17:31:34ZProximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade10.1038/ncomms139822041-1723https://doaj.org/article/44331a73a8a447e48a8689599bc13ffd2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13982https://doaj.org/toc/2041-1723The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface.Yifei ZhangStanislav TsitkovHenry HessNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yifei Zhang
Stanislav Tsitkov
Henry Hess
Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
description The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface.
format article
author Yifei Zhang
Stanislav Tsitkov
Henry Hess
author_facet Yifei Zhang
Stanislav Tsitkov
Henry Hess
author_sort Yifei Zhang
title Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
title_short Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
title_full Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
title_fullStr Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
title_full_unstemmed Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
title_sort proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/44331a73a8a447e48a8689599bc13ffd
work_keys_str_mv AT yifeizhang proximitydoesnotcontributetoactivityenhancementintheglucoseoxidasehorseradishperoxidasecascade
AT stanislavtsitkov proximitydoesnotcontributetoactivityenhancementintheglucoseoxidasehorseradishperoxidasecascade
AT henryhess proximitydoesnotcontributetoactivityenhancementintheglucoseoxidasehorseradishperoxidasecascade
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