Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade
The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface.
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Nature Portfolio
2016
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oai:doaj.org-article:44331a73a8a447e48a8689599bc13ffd2021-12-02T17:31:34ZProximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade10.1038/ncomms139822041-1723https://doaj.org/article/44331a73a8a447e48a8689599bc13ffd2016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13982https://doaj.org/toc/2041-1723The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface.Yifei ZhangStanislav TsitkovHenry HessNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
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Science Q Yifei Zhang Stanislav Tsitkov Henry Hess Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade |
description |
The activity enhancement of the glucose oxide and horseradish peroxidase enzymatic cascade on DNA scaffolds has been linked to proximity effects. Here, the authors challenge this view and suggest that the activity improvement is rather due to the pH near the DNA surface. |
format |
article |
author |
Yifei Zhang Stanislav Tsitkov Henry Hess |
author_facet |
Yifei Zhang Stanislav Tsitkov Henry Hess |
author_sort |
Yifei Zhang |
title |
Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade |
title_short |
Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade |
title_full |
Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade |
title_fullStr |
Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade |
title_full_unstemmed |
Proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade |
title_sort |
proximity does not contribute to activity enhancement in the glucose oxidase–horseradish peroxidase cascade |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/44331a73a8a447e48a8689599bc13ffd |
work_keys_str_mv |
AT yifeizhang proximitydoesnotcontributetoactivityenhancementintheglucoseoxidasehorseradishperoxidasecascade AT stanislavtsitkov proximitydoesnotcontributetoactivityenhancementintheglucoseoxidasehorseradishperoxidasecascade AT henryhess proximitydoesnotcontributetoactivityenhancementintheglucoseoxidasehorseradishperoxidasecascade |
_version_ |
1718380548438622208 |