Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking

Understanding nanomaterials interactions with complement is important for a number of applications. Here, the authors study the interaction of sub 6 nm dendrimers with complement and show the small dendrimers escape complement activation but do interact with IgM to trigger lectin-pathway complement...

Full description

Saved in:
Bibliographic Details
Main Authors: Lin-Ping Wu, Mario Ficker, Jørn B. Christensen, Dmitri Simberg, Panagiotis N. Trohopoulos, Seyed M. Moghimi
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/4434bb5d9dfb49f59c75cce00c6a6d84
Tags: Add Tag
No Tags, Be the first to tag this record!