AGES AND SEX DEPENDENCE OF SPECIFIC IMMUNE RESPONSE IN THE PERSONS INOCULATED WITH TICKSBORNE ENCEPHALITIS VACCINE

Abstract. Immunological efficiency of the tick-borne encephalitis (TBE) vaccine Encepur® Adult (Chiron Behring GmbH, Germany) was studied according to the sex- and age stratification of inoculated persons. The group under observation consisted of 117 residents of Vladivostok, Russian Far East, 17 to...

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Autores principales:	G. N. Leonova, E. V. Pavlenko, N. V. Krylova, O. S. Maystrovskaya, N. V. Kovalchuk
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	vaccine tick-borne encephalitis elisa vaccination Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/44381bbc3c514cbc8cefa232705d73ad
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spelling	oai:doaj.org-article:44381bbc3c514cbc8cefa232705d73ad2021-11-18T08:03:41ZAGES AND SEX DEPENDENCE OF SPECIFIC IMMUNE RESPONSE IN THE PERSONS INOCULATED WITH TICKSBORNE ENCEPHALITIS VACCINE1563-06252313-741X10.15789/1563-0625-2006-1-73-80https://doaj.org/article/44381bbc3c514cbc8cefa232705d73ad2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/436https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Immunological efficiency of the tick-borne encephalitis (TBE) vaccine Encepur® Adult (Chiron Behring GmbH, Germany) was studied according to the sex- and age stratification of inoculated persons. The group under observation consisted of 117 residents of Vladivostok, Russian Far East, 17 to 68 years old, in whom anti-TBE antibodies were not detectable. Vaccination was performed according to the classical schedule, i.e., 0 days-28 days-12 months. Specific immune response was evaluated before vaccination, a month after first inoculation, 1 month following second vaccination, 1 year after two inoculations, and a month after third vaccination. Total index of marked immunological protection reached 100% after the 3rd vaccination. The highest response rates were revealed in young subjects and women. It was shown that the male persons from young and mature age groups travel to the forest more commonly than females, as opposed to the appropriate groups at older ages. However, in the older age group we have reversed situation. These data substantiate application of the tick-borne encephalitis vaccine Encepur® Adult as an effective mean for TBE prevention in endemic areas of Russia, where different strains of TBE virus are encountered.G. N. LeonovaE. V. PavlenkoN. V. KrylovaO. S. MaystrovskayaN. V. KovalchukSPb RAACIarticlevaccinetick-borne encephalitiselisavaccinationImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 8, Iss 1, Pp 73-80 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	vaccine tick-borne encephalitis elisa vaccination Immunologic diseases. Allergy RC581-607
spellingShingle	vaccine tick-borne encephalitis elisa vaccination Immunologic diseases. Allergy RC581-607 G. N. Leonova E. V. Pavlenko N. V. Krylova O. S. Maystrovskaya N. V. Kovalchuk AGES AND SEX DEPENDENCE OF SPECIFIC IMMUNE RESPONSE IN THE PERSONS INOCULATED WITH TICKSBORNE ENCEPHALITIS VACCINE
description	Abstract. Immunological efficiency of the tick-borne encephalitis (TBE) vaccine Encepur® Adult (Chiron Behring GmbH, Germany) was studied according to the sex- and age stratification of inoculated persons. The group under observation consisted of 117 residents of Vladivostok, Russian Far East, 17 to 68 years old, in whom anti-TBE antibodies were not detectable. Vaccination was performed according to the classical schedule, i.e., 0 days-28 days-12 months. Specific immune response was evaluated before vaccination, a month after first inoculation, 1 month following second vaccination, 1 year after two inoculations, and a month after third vaccination. Total index of marked immunological protection reached 100% after the 3rd vaccination. The highest response rates were revealed in young subjects and women. It was shown that the male persons from young and mature age groups travel to the forest more commonly than females, as opposed to the appropriate groups at older ages. However, in the older age group we have reversed situation. These data substantiate application of the tick-borne encephalitis vaccine Encepur® Adult as an effective mean for TBE prevention in endemic areas of Russia, where different strains of TBE virus are encountered.
format	article
author	G. N. Leonova E. V. Pavlenko N. V. Krylova O. S. Maystrovskaya N. V. Kovalchuk
author_facet	G. N. Leonova E. V. Pavlenko N. V. Krylova O. S. Maystrovskaya N. V. Kovalchuk
author_sort	G. N. Leonova
title	AGES AND SEX DEPENDENCE OF SPECIFIC IMMUNE RESPONSE IN THE PERSONS INOCULATED WITH TICKSBORNE ENCEPHALITIS VACCINE
title_short	AGES AND SEX DEPENDENCE OF SPECIFIC IMMUNE RESPONSE IN THE PERSONS INOCULATED WITH TICKSBORNE ENCEPHALITIS VACCINE
title_full	AGES AND SEX DEPENDENCE OF SPECIFIC IMMUNE RESPONSE IN THE PERSONS INOCULATED WITH TICKSBORNE ENCEPHALITIS VACCINE
title_fullStr	AGES AND SEX DEPENDENCE OF SPECIFIC IMMUNE RESPONSE IN THE PERSONS INOCULATED WITH TICKSBORNE ENCEPHALITIS VACCINE
title_full_unstemmed	AGES AND SEX DEPENDENCE OF SPECIFIC IMMUNE RESPONSE IN THE PERSONS INOCULATED WITH TICKSBORNE ENCEPHALITIS VACCINE
title_sort	ages and sex dependence of specific immune response in the persons inoculated with ticksborne encephalitis vaccine
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/44381bbc3c514cbc8cefa232705d73ad
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AGES AND SEX DEPENDENCE OF SPECIFIC IMMUNE RESPONSE IN THE PERSONS INOCULATED WITH TICKSBORNE ENCEPHALITIS VACCINE

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