Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy

Mild photothermal therapy can be used to induce a favourable immunological response. In this study, the authors combine a photothermal therapy sensitizer and anti-PD-L1 into a lipid gel and find that, on controlled delivery to tumours, it potentiates anti-PD therapy and boosts anticancer efficacy.

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Autores principales: Liping Huang, Yanan Li, Yunai Du, Yiyi Zhang, Xiuxia Wang, Yuan Ding, Xiangliang Yang, Fanling Meng, Jiasheng Tu, Liang Luo, Chunmeng Sun
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/4446994f128e4030b3e5cebdeaaa42a6
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spelling oai:doaj.org-article:4446994f128e4030b3e5cebdeaaa42a62021-12-02T16:58:03ZMild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy10.1038/s41467-019-12771-92041-1723https://doaj.org/article/4446994f128e4030b3e5cebdeaaa42a62019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12771-9https://doaj.org/toc/2041-1723Mild photothermal therapy can be used to induce a favourable immunological response. In this study, the authors combine a photothermal therapy sensitizer and anti-PD-L1 into a lipid gel and find that, on controlled delivery to tumours, it potentiates anti-PD therapy and boosts anticancer efficacy.Liping HuangYanan LiYunai DuYiyi ZhangXiuxia WangYuan DingXiangliang YangFanling MengJiasheng TuLiang LuoChunmeng SunNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Liping Huang
Yanan Li
Yunai Du
Yiyi Zhang
Xiuxia Wang
Yuan Ding
Xiangliang Yang
Fanling Meng
Jiasheng Tu
Liang Luo
Chunmeng Sun
Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy
description Mild photothermal therapy can be used to induce a favourable immunological response. In this study, the authors combine a photothermal therapy sensitizer and anti-PD-L1 into a lipid gel and find that, on controlled delivery to tumours, it potentiates anti-PD therapy and boosts anticancer efficacy.
format article
author Liping Huang
Yanan Li
Yunai Du
Yiyi Zhang
Xiuxia Wang
Yuan Ding
Xiangliang Yang
Fanling Meng
Jiasheng Tu
Liang Luo
Chunmeng Sun
author_facet Liping Huang
Yanan Li
Yunai Du
Yiyi Zhang
Xiuxia Wang
Yuan Ding
Xiangliang Yang
Fanling Meng
Jiasheng Tu
Liang Luo
Chunmeng Sun
author_sort Liping Huang
title Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy
title_short Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy
title_full Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy
title_fullStr Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy
title_full_unstemmed Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy
title_sort mild photothermal therapy potentiates anti-pd-l1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/4446994f128e4030b3e5cebdeaaa42a6
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