Variability in mRNA translation: a random matrix theory approach

Abstract The rate of mRNA translation depends on the initiation, elongation, and termination rates of ribosomes along the mRNA. These rates depend on many “local” factors like the abundance of free ribosomes and tRNA molecules in the vicinity of the mRNA molecule. All these factors are stochastic an...

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Autores principales: Michael Margaliot, Wasim Huleihel, Tamir Tuller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/444da30749464f0a930644f1049d60c7
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