A prospective study of risk factors for cardiovascular events among the elderly

Marcos Aparecido Sarria Cabrera,1 Selma Maffei de Andrade,2 Arthur Eumann Mesas21Discipline of Geriatrics, Postgraduate Program in Public Health, 2Department of Public Health, Postgraduate Program in Public Health, Universidade Estadual de Londrina, Paraná, BrazilObjective: To analyze the...

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Autores principales:	Cabrera MA, Andrade SM, Mesas AE
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	aged cardiovascular diseases risk factors epidemiology Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/4457707493a04c24b69b746a4f3555d8
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spelling	oai:doaj.org-article:4457707493a04c24b69b746a4f3555d82021-12-02T01:43:00ZA prospective study of risk factors for cardiovascular events among the elderly1178-1998https://doaj.org/article/4457707493a04c24b69b746a4f3555d82012-11-01T00:00:00Zhttps://www.dovepress.com/a-prospective-study-of-risk-factors-for-cardiovascular-events-among-th-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Marcos Aparecido Sarria Cabrera,1 Selma Maffei de Andrade,2 Arthur Eumann Mesas21Discipline of Geriatrics, Postgraduate Program in Public Health, 2Department of Public Health, Postgraduate Program in Public Health, Universidade Estadual de Londrina, Paraná, BrazilObjective: To analyze the impact of cardiovascular (CV) risk factors on the occurrence of fatal and non-fatal CV events in elderly individuals.Methods: The present research was a prospective cohort study of 800 elderly Brazilian outpatients (60 to 85 years old) with a 12-year follow-up period (baseline: 1997–1998). The outcome variable was CV mortality or non-fatal CV events (stroke, infarction, angina, heart failure). Hypertension, diabetes, global and abdominal obesity, dyslipidemias, and metabolic syndrome were analyzed as independent variables. The analyses were based on Cox proportional hazard models and adjusted for gender, age range, smoking, regular physical activity, and previous cardiovascular disease.Results: A total of 233 fatal and non-fatal CV events were observed (29.1%). In the adjusted analysis, the following variables were associated with CV risk: hypertension hazard ratio (HR): 1.69; confidence interval (CI) 95%: 1.28–2.24, diabetes (HR: 2.67; CI 95%: 1.98–3.61), metabolic syndrome (HR: 1.61; CI 95%: 1.24–2.09), abdominal obesity (HR: 1.36; CI 95%: 1.03–1.79), hypertriglyceridemia (HR: 1.67; CI 95%: 1.22–2.30) and high triglyceride/HDL-c ratio (HR: 1.73; CI 95%: 1.31–2.84). Hypertension, diabetes, and dyslipidemia remained associated with CV risk regardless of abdominal obesity.Conclusion: In this prospective study, hypertension, diabetes, metabolic syndrome, abdominal obesity, and hypertriglyceridemia were predictors of CV risk in elderly individuals. These results confirm the relevance of controlling these CV risk factors in this age group.Keywords: aged, cardiovascular diseases, risk factors, epidemiologyCabrera MAAndrade SMMesas AEDove Medical Pressarticleagedcardiovascular diseasesrisk factorsepidemiologyGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 7, Pp 463-468 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	aged cardiovascular diseases risk factors epidemiology Geriatrics RC952-954.6
spellingShingle	aged cardiovascular diseases risk factors epidemiology Geriatrics RC952-954.6 Cabrera MA Andrade SM Mesas AE A prospective study of risk factors for cardiovascular events among the elderly
description	Marcos Aparecido Sarria Cabrera,1 Selma Maffei de Andrade,2 Arthur Eumann Mesas21Discipline of Geriatrics, Postgraduate Program in Public Health, 2Department of Public Health, Postgraduate Program in Public Health, Universidade Estadual de Londrina, Paraná, BrazilObjective: To analyze the impact of cardiovascular (CV) risk factors on the occurrence of fatal and non-fatal CV events in elderly individuals.Methods: The present research was a prospective cohort study of 800 elderly Brazilian outpatients (60 to 85 years old) with a 12-year follow-up period (baseline: 1997–1998). The outcome variable was CV mortality or non-fatal CV events (stroke, infarction, angina, heart failure). Hypertension, diabetes, global and abdominal obesity, dyslipidemias, and metabolic syndrome were analyzed as independent variables. The analyses were based on Cox proportional hazard models and adjusted for gender, age range, smoking, regular physical activity, and previous cardiovascular disease.Results: A total of 233 fatal and non-fatal CV events were observed (29.1%). In the adjusted analysis, the following variables were associated with CV risk: hypertension hazard ratio (HR): 1.69; confidence interval (CI) 95%: 1.28–2.24, diabetes (HR: 2.67; CI 95%: 1.98–3.61), metabolic syndrome (HR: 1.61; CI 95%: 1.24–2.09), abdominal obesity (HR: 1.36; CI 95%: 1.03–1.79), hypertriglyceridemia (HR: 1.67; CI 95%: 1.22–2.30) and high triglyceride/HDL-c ratio (HR: 1.73; CI 95%: 1.31–2.84). Hypertension, diabetes, and dyslipidemia remained associated with CV risk regardless of abdominal obesity.Conclusion: In this prospective study, hypertension, diabetes, metabolic syndrome, abdominal obesity, and hypertriglyceridemia were predictors of CV risk in elderly individuals. These results confirm the relevance of controlling these CV risk factors in this age group.Keywords: aged, cardiovascular diseases, risk factors, epidemiology
format	article
author	Cabrera MA Andrade SM Mesas AE
author_facet	Cabrera MA Andrade SM Mesas AE
author_sort	Cabrera MA
title	A prospective study of risk factors for cardiovascular events among the elderly
title_short	A prospective study of risk factors for cardiovascular events among the elderly
title_full	A prospective study of risk factors for cardiovascular events among the elderly
title_fullStr	A prospective study of risk factors for cardiovascular events among the elderly
title_full_unstemmed	A prospective study of risk factors for cardiovascular events among the elderly
title_sort	prospective study of risk factors for cardiovascular events among the elderly
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/4457707493a04c24b69b746a4f3555d8
work_keys_str_mv	AT cabrerama aprospectivestudyofriskfactorsforcardiovasculareventsamongtheelderly AT andradesm aprospectivestudyofriskfactorsforcardiovasculareventsamongtheelderly AT mesasae aprospectivestudyofriskfactorsforcardiovasculareventsamongtheelderly AT cabrerama prospectivestudyofriskfactorsforcardiovasculareventsamongtheelderly AT andradesm prospectivestudyofriskfactorsforcardiovasculareventsamongtheelderly AT mesasae prospectivestudyofriskfactorsforcardiovasculareventsamongtheelderly
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A prospective study of risk factors for cardiovascular events among the elderly

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