ASSOCIATION BETWEEN PHENOTYPE OF PERIPHERAL MONONUCLEAR CELLS AND HISTOPATHOLOGIC FEATURES OF GASTROINTESTINAL MALIGNANСIES

Abstract. The contents of peripheral blood cells expressing activation markers are increased in patients with gastrointestinal malignancies, mostly in cases of gastric cancer. An association is revealed between the immunological parameters and histopathological features. Absolute contents of lymphoc...

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Autores principales: A. I. Autenshlus, A. V. Sosnina, E. S. Mikhailova, A. P. Lykov, D. V. Morozov, O. R. Tikholis, R. V. Shorokhov, S. V. Michurina
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Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/445881c1bb63426b8389315a5e603d85
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spelling oai:doaj.org-article:445881c1bb63426b8389315a5e603d852021-11-18T08:03:38ZASSOCIATION BETWEEN PHENOTYPE OF PERIPHERAL MONONUCLEAR CELLS AND HISTOPATHOLOGIC FEATURES OF GASTROINTESTINAL MALIGNANСIES1563-06252313-741X10.15789/1563-0625-2008-2-3-181-186https://doaj.org/article/445881c1bb63426b8389315a5e603d852014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/123https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. The contents of peripheral blood cells expressing activation markers are increased in patients with gastrointestinal malignancies, mostly in cases of gastric cancer. An association is revealed between the immunological parameters and histopathological features. Absolute contents of lymphocytes with CD71+ and HLA-DR+ phenotype, showing a significantly correlation with most pathological parameters of gastric tumors, may be considered as an informative marker of tumor progression at pre-surgical step. (Med. Immunol., 2008, vol. 10, N 2-3, pp 181-186).A. I. AutenshlusA. V. SosninaE. S. MikhailovaA. P. LykovD. V. MorozovO. R. TikholisR. V. ShorokhovS. V. MichurinaSPb RAACIarticlemononuclear cells phenotypegastrointestinal malignanciesImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 10, Iss 2-3, Pp 181-186 (2014)
institution DOAJ
collection DOAJ
language RU
topic mononuclear cells phenotype
gastrointestinal malignancies
Immunologic diseases. Allergy
RC581-607
spellingShingle mononuclear cells phenotype
gastrointestinal malignancies
Immunologic diseases. Allergy
RC581-607
A. I. Autenshlus
A. V. Sosnina
E. S. Mikhailova
A. P. Lykov
D. V. Morozov
O. R. Tikholis
R. V. Shorokhov
S. V. Michurina
ASSOCIATION BETWEEN PHENOTYPE OF PERIPHERAL MONONUCLEAR CELLS AND HISTOPATHOLOGIC FEATURES OF GASTROINTESTINAL MALIGNANСIES
description Abstract. The contents of peripheral blood cells expressing activation markers are increased in patients with gastrointestinal malignancies, mostly in cases of gastric cancer. An association is revealed between the immunological parameters and histopathological features. Absolute contents of lymphocytes with CD71+ and HLA-DR+ phenotype, showing a significantly correlation with most pathological parameters of gastric tumors, may be considered as an informative marker of tumor progression at pre-surgical step. (Med. Immunol., 2008, vol. 10, N 2-3, pp 181-186).
format article
author A. I. Autenshlus
A. V. Sosnina
E. S. Mikhailova
A. P. Lykov
D. V. Morozov
O. R. Tikholis
R. V. Shorokhov
S. V. Michurina
author_facet A. I. Autenshlus
A. V. Sosnina
E. S. Mikhailova
A. P. Lykov
D. V. Morozov
O. R. Tikholis
R. V. Shorokhov
S. V. Michurina
author_sort A. I. Autenshlus
title ASSOCIATION BETWEEN PHENOTYPE OF PERIPHERAL MONONUCLEAR CELLS AND HISTOPATHOLOGIC FEATURES OF GASTROINTESTINAL MALIGNANСIES
title_short ASSOCIATION BETWEEN PHENOTYPE OF PERIPHERAL MONONUCLEAR CELLS AND HISTOPATHOLOGIC FEATURES OF GASTROINTESTINAL MALIGNANСIES
title_full ASSOCIATION BETWEEN PHENOTYPE OF PERIPHERAL MONONUCLEAR CELLS AND HISTOPATHOLOGIC FEATURES OF GASTROINTESTINAL MALIGNANСIES
title_fullStr ASSOCIATION BETWEEN PHENOTYPE OF PERIPHERAL MONONUCLEAR CELLS AND HISTOPATHOLOGIC FEATURES OF GASTROINTESTINAL MALIGNANСIES
title_full_unstemmed ASSOCIATION BETWEEN PHENOTYPE OF PERIPHERAL MONONUCLEAR CELLS AND HISTOPATHOLOGIC FEATURES OF GASTROINTESTINAL MALIGNANСIES
title_sort association between phenotype of peripheral mononuclear cells and histopathologic features of gastrointestinal malignanсies
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/445881c1bb63426b8389315a5e603d85
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