Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer

The number of usable light-responsive enzymes is limited, despite the potential biotechnological applications. Here, the authors report a flavoprotein monooxygenase which is controllable by blue light illumination, and propose a mechanism involving protein-mediated radical photoreduction of FAD via...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Simon Ernst, Stefano Rovida, Andrea Mattevi, Susanne Fetzner, Steffen L. Drees
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/446dcc8c776447e7b172e6e017c89475
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:446dcc8c776447e7b172e6e017c89475
record_format	dspace
spelling	oai:doaj.org-article:446dcc8c776447e7b172e6e017c894752021-12-02T15:00:13ZPhotoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer10.1038/s41467-020-16450-y2041-1723https://doaj.org/article/446dcc8c776447e7b172e6e017c894752020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16450-yhttps://doaj.org/toc/2041-1723The number of usable light-responsive enzymes is limited, despite the potential biotechnological applications. Here, the authors report a flavoprotein monooxygenase which is controllable by blue light illumination, and propose a mechanism involving protein-mediated radical photoreduction of FAD via a semiquinone intermediate.Simon ErnstStefano RovidaAndrea MatteviSusanne FetznerSteffen L. DreesNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Simon Ernst Stefano Rovida Andrea Mattevi Susanne Fetzner Steffen L. Drees Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer
description	The number of usable light-responsive enzymes is limited, despite the potential biotechnological applications. Here, the authors report a flavoprotein monooxygenase which is controllable by blue light illumination, and propose a mechanism involving protein-mediated radical photoreduction of FAD via a semiquinone intermediate.
format	article
author	Simon Ernst Stefano Rovida Andrea Mattevi Susanne Fetzner Steffen L. Drees
author_facet	Simon Ernst Stefano Rovida Andrea Mattevi Susanne Fetzner Steffen L. Drees
author_sort	Simon Ernst
title	Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer
title_short	Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer
title_full	Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer
title_fullStr	Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer
title_full_unstemmed	Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer
title_sort	photoinduced monooxygenation involving nad(p)h-fad sequential single-electron transfer
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/446dcc8c776447e7b172e6e017c89475
work_keys_str_mv	AT simonernst photoinducedmonooxygenationinvolvingnadphfadsequentialsingleelectrontransfer AT stefanorovida photoinducedmonooxygenationinvolvingnadphfadsequentialsingleelectrontransfer AT andreamattevi photoinducedmonooxygenationinvolvingnadphfadsequentialsingleelectrontransfer AT susannefetzner photoinducedmonooxygenationinvolvingnadphfadsequentialsingleelectrontransfer AT steffenldrees photoinducedmonooxygenationinvolvingnadphfadsequentialsingleelectrontransfer
_version_	1718389195636998144

Photoinduced monooxygenation involving NAD(P)H-FAD sequential single-electron transfer

Ejemplares similares