Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism

RORγt is known to play critical roles in the regulation of a number of immune cell subsets. Here the authors implicate mitochondrial transcription factor A in the regulation of intestinal RORγt + lymphocyte homeostasis and metabolic control in a murine in vivo model.

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Detalles Bibliográficos
Autores principales: Zheng Fu, Joseph W. Dean, Lifeng Xiong, Michael W. Dougherty, Kristen N. Oliff, Zong-ming E. Chen, Christian Jobin, Timothy J. Garrett, Liang Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/446f53463c9844739ef9f5446fb56343
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Sumario:RORγt is known to play critical roles in the regulation of a number of immune cell subsets. Here the authors implicate mitochondrial transcription factor A in the regulation of intestinal RORγt + lymphocyte homeostasis and metabolic control in a murine in vivo model.