Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism

RORγt is known to play critical roles in the regulation of a number of immune cell subsets. Here the authors implicate mitochondrial transcription factor A in the regulation of intestinal RORγt + lymphocyte homeostasis and metabolic control in a murine in vivo model.

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Autores principales:	Zheng Fu, Joseph W. Dean, Lifeng Xiong, Michael W. Dougherty, Kristen N. Oliff, Zong-ming E. Chen, Christian Jobin, Timothy J. Garrett, Liang Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/446f53463c9844739ef9f5446fb56343
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spelling	oai:doaj.org-article:446f53463c9844739ef9f5446fb563432021-12-02T16:43:36ZMitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism10.1038/s41467-021-24755-92041-1723https://doaj.org/article/446f53463c9844739ef9f5446fb563432021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24755-9https://doaj.org/toc/2041-1723RORγt is known to play critical roles in the regulation of a number of immune cell subsets. Here the authors implicate mitochondrial transcription factor A in the regulation of intestinal RORγt + lymphocyte homeostasis and metabolic control in a murine in vivo model.Zheng FuJoseph W. DeanLifeng XiongMichael W. DoughertyKristen N. OliffZong-ming E. ChenChristian JobinTimothy J. GarrettLiang ZhouNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zheng Fu Joseph W. Dean Lifeng Xiong Michael W. Dougherty Kristen N. Oliff Zong-ming E. Chen Christian Jobin Timothy J. Garrett Liang Zhou Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism
description	RORγt is known to play critical roles in the regulation of a number of immune cell subsets. Here the authors implicate mitochondrial transcription factor A in the regulation of intestinal RORγt + lymphocyte homeostasis and metabolic control in a murine in vivo model.
format	article
author	Zheng Fu Joseph W. Dean Lifeng Xiong Michael W. Dougherty Kristen N. Oliff Zong-ming E. Chen Christian Jobin Timothy J. Garrett Liang Zhou
author_facet	Zheng Fu Joseph W. Dean Lifeng Xiong Michael W. Dougherty Kristen N. Oliff Zong-ming E. Chen Christian Jobin Timothy J. Garrett Liang Zhou
author_sort	Zheng Fu
title	Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism
title_short	Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism
title_full	Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism
title_fullStr	Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism
title_full_unstemmed	Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism
title_sort	mitochondrial transcription factor a in rorγt+ lymphocytes regulate small intestine homeostasis and metabolism
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/446f53463c9844739ef9f5446fb56343
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Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism

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