Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry

SWATH-mass spectrometry consists of a data-independent acquisition and a targeted data analysis strategy that aims to maintain the favorable quantitative characteristics on the scale of thousands of proteins. Here, using data generated by eleven groups worldwide, the authors show that SWATH-MS is ca...

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Autores principales: Ben C. Collins, Christie L. Hunter, Yansheng Liu, Birgit Schilling, George Rosenberger, Samuel L. Bader, Daniel W. Chan, Bradford W. Gibson, Anne-Claude Gingras, Jason M. Held, Mio Hirayama-Kurogi, Guixue Hou, Christoph Krisp, Brett Larsen, Liang Lin, Siqi Liu, Mark P. Molloy, Robert L. Moritz, Sumio Ohtsuki, Ralph Schlapbach, Nathalie Selevsek, Stefani N. Thomas, Shin-Cheng Tzeng, Hui Zhang, Ruedi Aebersold
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Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/44740b6f8c2d466ca5462d8455eae709
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spelling oai:doaj.org-article:44740b6f8c2d466ca5462d8455eae7092021-12-02T13:23:47ZMulti-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry10.1038/s41467-017-00249-52041-1723https://doaj.org/article/44740b6f8c2d466ca5462d8455eae7092017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00249-5https://doaj.org/toc/2041-1723SWATH-mass spectrometry consists of a data-independent acquisition and a targeted data analysis strategy that aims to maintain the favorable quantitative characteristics on the scale of thousands of proteins. Here, using data generated by eleven groups worldwide, the authors show that SWATH-MS is capable of generating highly reproducible data across different laboratories.Ben C. CollinsChristie L. HunterYansheng LiuBirgit SchillingGeorge RosenbergerSamuel L. BaderDaniel W. ChanBradford W. GibsonAnne-Claude GingrasJason M. HeldMio Hirayama-KurogiGuixue HouChristoph KrispBrett LarsenLiang LinSiqi LiuMark P. MolloyRobert L. MoritzSumio OhtsukiRalph SchlapbachNathalie SelevsekStefani N. ThomasShin-Cheng TzengHui ZhangRuedi AebersoldNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ben C. Collins
Christie L. Hunter
Yansheng Liu
Birgit Schilling
George Rosenberger
Samuel L. Bader
Daniel W. Chan
Bradford W. Gibson
Anne-Claude Gingras
Jason M. Held
Mio Hirayama-Kurogi
Guixue Hou
Christoph Krisp
Brett Larsen
Liang Lin
Siqi Liu
Mark P. Molloy
Robert L. Moritz
Sumio Ohtsuki
Ralph Schlapbach
Nathalie Selevsek
Stefani N. Thomas
Shin-Cheng Tzeng
Hui Zhang
Ruedi Aebersold
Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry
description SWATH-mass spectrometry consists of a data-independent acquisition and a targeted data analysis strategy that aims to maintain the favorable quantitative characteristics on the scale of thousands of proteins. Here, using data generated by eleven groups worldwide, the authors show that SWATH-MS is capable of generating highly reproducible data across different laboratories.
format article
author Ben C. Collins
Christie L. Hunter
Yansheng Liu
Birgit Schilling
George Rosenberger
Samuel L. Bader
Daniel W. Chan
Bradford W. Gibson
Anne-Claude Gingras
Jason M. Held
Mio Hirayama-Kurogi
Guixue Hou
Christoph Krisp
Brett Larsen
Liang Lin
Siqi Liu
Mark P. Molloy
Robert L. Moritz
Sumio Ohtsuki
Ralph Schlapbach
Nathalie Selevsek
Stefani N. Thomas
Shin-Cheng Tzeng
Hui Zhang
Ruedi Aebersold
author_facet Ben C. Collins
Christie L. Hunter
Yansheng Liu
Birgit Schilling
George Rosenberger
Samuel L. Bader
Daniel W. Chan
Bradford W. Gibson
Anne-Claude Gingras
Jason M. Held
Mio Hirayama-Kurogi
Guixue Hou
Christoph Krisp
Brett Larsen
Liang Lin
Siqi Liu
Mark P. Molloy
Robert L. Moritz
Sumio Ohtsuki
Ralph Schlapbach
Nathalie Selevsek
Stefani N. Thomas
Shin-Cheng Tzeng
Hui Zhang
Ruedi Aebersold
author_sort Ben C. Collins
title Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry
title_short Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry
title_full Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry
title_fullStr Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry
title_full_unstemmed Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry
title_sort multi-laboratory assessment of reproducibility, qualitative and quantitative performance of swath-mass spectrometry
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/44740b6f8c2d466ca5462d8455eae709
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