Connexin 43 is required for the maintenance of mitochondrial integrity in brown adipose tissue

Connexin 43 is required for the maintenance of mitochondrial integrity in brown adipose tissue

Abstract We investigated the role of connexin 43 (Cx43) in maintaining the integrity of mitochondria in brown adipose tissue (BAT). The functional effects of Cx43 were evaluated using inducible, adipocyte-specific Cx43 knockout in mice (Gja1 adipoq KO) and by overexpression and knockdown of Cx43 in...

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Main Authors: Sang-Nam Kim, Hyun-Jung Kwon, Seo-Woo Im, Yeon-Ho Son, Seun Akindehin, Young-Suk Jung, Se Jeong Lee, Im Joo Rhyu, Il Yong Kim, Je-Kyoung Seong, Jinu Lee, Hee-Chan Yoo, James G. Granneman, Yun-Hee Lee
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/447d2147654f468aa1f2190154e48614
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https://doaj.org/article/447d2147654f468aa1f2190154e48614

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