Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability

Measuring the size distribution of nanomaterials in biological fluids is crucial to understand their properties in vivo. Here, the authors apply fluorescence recovery after photobleaching to measure protein aggregation in serum and to study permeability of biological membranes in mouse models.

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Autores principales: Ranhua Xiong, Roosmarijn E. Vandenbroucke, Katleen Broos, Toon Brans, Elien Van Wonterghem, Claude Libert, Jo Demeester, Stefaan C. De Smedt, Kevin Braeckmans
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/4489899247274c518a87bcf6d594dca1
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spelling oai:doaj.org-article:4489899247274c518a87bcf6d594dca12021-12-02T17:32:20ZSizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability10.1038/ncomms129822041-1723https://doaj.org/article/4489899247274c518a87bcf6d594dca12016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12982https://doaj.org/toc/2041-1723Measuring the size distribution of nanomaterials in biological fluids is crucial to understand their properties in vivo. Here, the authors apply fluorescence recovery after photobleaching to measure protein aggregation in serum and to study permeability of biological membranes in mouse models.Ranhua XiongRoosmarijn E. VandenbrouckeKatleen BroosToon BransElien Van WonterghemClaude LibertJo DemeesterStefaan C. De SmedtKevin BraeckmansNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ranhua Xiong
Roosmarijn E. Vandenbroucke
Katleen Broos
Toon Brans
Elien Van Wonterghem
Claude Libert
Jo Demeester
Stefaan C. De Smedt
Kevin Braeckmans
Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability
description Measuring the size distribution of nanomaterials in biological fluids is crucial to understand their properties in vivo. Here, the authors apply fluorescence recovery after photobleaching to measure protein aggregation in serum and to study permeability of biological membranes in mouse models.
format article
author Ranhua Xiong
Roosmarijn E. Vandenbroucke
Katleen Broos
Toon Brans
Elien Van Wonterghem
Claude Libert
Jo Demeester
Stefaan C. De Smedt
Kevin Braeckmans
author_facet Ranhua Xiong
Roosmarijn E. Vandenbroucke
Katleen Broos
Toon Brans
Elien Van Wonterghem
Claude Libert
Jo Demeester
Stefaan C. De Smedt
Kevin Braeckmans
author_sort Ranhua Xiong
title Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability
title_short Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability
title_full Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability
title_fullStr Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability
title_full_unstemmed Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability
title_sort sizing nanomaterials in bio-fluids by cfrap enables protein aggregation measurements and diagnosis of bio-barrier permeability
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/4489899247274c518a87bcf6d594dca1
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