Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time

The circadian clock proteins KaiA, KaiB, and KaiC reconstitute a circa-24 h oscillation of KaiC phosphorylation in vitro. Here the authors use high-speed atomic force microscopy to visualize in real time and quantify the dynamic interactions of KaiA with KaiC on the sub-second timescale to discover...

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Autores principales:	Tetsuya Mori, Shogo Sugiyama, Mark Byrne, Carl Hirschie Johnson, Takayuki Uchihashi, Toshio Ando
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/449004dac2544cb1b23b08abbadf63e7
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spelling	oai:doaj.org-article:449004dac2544cb1b23b08abbadf63e72021-12-02T17:32:33ZRevealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time10.1038/s41467-018-05438-42041-1723https://doaj.org/article/449004dac2544cb1b23b08abbadf63e72018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05438-4https://doaj.org/toc/2041-1723The circadian clock proteins KaiA, KaiB, and KaiC reconstitute a circa-24 h oscillation of KaiC phosphorylation in vitro. Here the authors use high-speed atomic force microscopy to visualize in real time and quantify the dynamic interactions of KaiA with KaiC on the sub-second timescale to discover mechanisms of oscillatory resilience.Tetsuya MoriShogo SugiyamaMark ByrneCarl Hirschie JohnsonTakayuki UchihashiToshio AndoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tetsuya Mori Shogo Sugiyama Mark Byrne Carl Hirschie Johnson Takayuki Uchihashi Toshio Ando Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time
description	The circadian clock proteins KaiA, KaiB, and KaiC reconstitute a circa-24 h oscillation of KaiC phosphorylation in vitro. Here the authors use high-speed atomic force microscopy to visualize in real time and quantify the dynamic interactions of KaiA with KaiC on the sub-second timescale to discover mechanisms of oscillatory resilience.
format	article
author	Tetsuya Mori Shogo Sugiyama Mark Byrne Carl Hirschie Johnson Takayuki Uchihashi Toshio Ando
author_facet	Tetsuya Mori Shogo Sugiyama Mark Byrne Carl Hirschie Johnson Takayuki Uchihashi Toshio Ando
author_sort	Tetsuya Mori
title	Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time
title_short	Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time
title_full	Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time
title_fullStr	Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time
title_full_unstemmed	Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time
title_sort	revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/449004dac2544cb1b23b08abbadf63e7
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Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time

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