Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time

The circadian clock proteins KaiA, KaiB, and KaiC reconstitute a circa-24 h oscillation of KaiC phosphorylation in vitro. Here the authors use high-speed atomic force microscopy to visualize in real time and quantify the dynamic interactions of KaiA with KaiC on the sub-second timescale to discover...

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Autores principales: Tetsuya Mori, Shogo Sugiyama, Mark Byrne, Carl Hirschie Johnson, Takayuki Uchihashi, Toshio Ando
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/449004dac2544cb1b23b08abbadf63e7
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