Adherence and rehospitalizations in patients with schizophrenia: evidence from Japanese claims data

Hiroyo Kuwabara,1 Yoshimichi Saito,1 Jörg Mahlich1,2 1Health Economics, Janssen KK, Tokyo, Japan; 2Düsseldorf Institute for Competition Economics, University of Düsseldorf, Düsseldorf, Germany Background: The aim of this study is to analyze if there is...

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Autores principales:	Kuwabara H, Saito Y, Mahlich J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/4493ca8a855848f9b9e259fb435944e6
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spelling	oai:doaj.org-article:4493ca8a855848f9b9e259fb435944e62021-12-02T02:04:54ZAdherence and rehospitalizations in patients with schizophrenia: evidence from Japanese claims data1178-2021https://doaj.org/article/4493ca8a855848f9b9e259fb435944e62015-04-01T00:00:00Zhttp://www.dovepress.com/adherence-and-rehospitalizations-in-patients-with-schizophrenia-eviden-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021 Hiroyo Kuwabara,1 Yoshimichi Saito,1 Jörg Mahlich1,2 1Health Economics, Janssen KK, Tokyo, Japan; 2Düsseldorf Institute for Competition Economics, University of Düsseldorf, Düsseldorf, Germany Background: The aim of this study is to analyze if there is a relationship between adherence to antipsychotic medication and rehospitalization for patients diagnosed with schizophrenia in Japan. Methods: Based on Japanese claims data, we constructed three patient groups based on their medication possession ratio (MPR). Controlling for potential confounders, a Cox proportional hazard model was employed to assess if medication adherence affects the risk of rehospitalization. Results: Patients with good adherence (MPRs from 0.8–1.1) had the lowest rates of admission. Both poor adherence (MPRs <0.8) and overadherence (MPRs >1.1) were associated with a significant higher risk of rehospitalization with hazard ratios of 4.7 and 2.0, respectively. Conclusion: The results of this study support the notion that good adherence to antipsychotic medication reduces the risk of rehospitalization of schizophrenia patients. Appropriate measures should be taken to improve adherence of schizophrenia patients. Keywords: adherence, hospitalizations, schizophrenia, Japan, claims data Kuwabara HSaito YMahlich JDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2015, Iss default, Pp 935-940 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Kuwabara H Saito Y Mahlich J Adherence and rehospitalizations in patients with schizophrenia: evidence from Japanese claims data
description	Hiroyo Kuwabara,1 Yoshimichi Saito,1 Jörg Mahlich1,2 1Health Economics, Janssen KK, Tokyo, Japan; 2Düsseldorf Institute for Competition Economics, University of Düsseldorf, Düsseldorf, Germany Background: The aim of this study is to analyze if there is a relationship between adherence to antipsychotic medication and rehospitalization for patients diagnosed with schizophrenia in Japan. Methods: Based on Japanese claims data, we constructed three patient groups based on their medication possession ratio (MPR). Controlling for potential confounders, a Cox proportional hazard model was employed to assess if medication adherence affects the risk of rehospitalization. Results: Patients with good adherence (MPRs from 0.8–1.1) had the lowest rates of admission. Both poor adherence (MPRs <0.8) and overadherence (MPRs >1.1) were associated with a significant higher risk of rehospitalization with hazard ratios of 4.7 and 2.0, respectively. Conclusion: The results of this study support the notion that good adherence to antipsychotic medication reduces the risk of rehospitalization of schizophrenia patients. Appropriate measures should be taken to improve adherence of schizophrenia patients. Keywords: adherence, hospitalizations, schizophrenia, Japan, claims data
format	article
author	Kuwabara H Saito Y Mahlich J
author_facet	Kuwabara H Saito Y Mahlich J
author_sort	Kuwabara H
title	Adherence and rehospitalizations in patients with schizophrenia: evidence from Japanese claims data
title_short	Adherence and rehospitalizations in patients with schizophrenia: evidence from Japanese claims data
title_full	Adherence and rehospitalizations in patients with schizophrenia: evidence from Japanese claims data
title_fullStr	Adherence and rehospitalizations in patients with schizophrenia: evidence from Japanese claims data
title_full_unstemmed	Adherence and rehospitalizations in patients with schizophrenia: evidence from Japanese claims data
title_sort	adherence and rehospitalizations in patients with schizophrenia: evidence from japanese claims data
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/4493ca8a855848f9b9e259fb435944e6
work_keys_str_mv	AT kuwabarah adherenceandrehospitalizationsinpatientswithschizophreniaevidencefromjapaneseclaimsdata AT saitoy adherenceandrehospitalizationsinpatientswithschizophreniaevidencefromjapaneseclaimsdata AT mahlichj adherenceandrehospitalizationsinpatientswithschizophreniaevidencefromjapaneseclaimsdata
_version_	1718402705541562368

Adherence and rehospitalizations in patients with schizophrenia: evidence from Japanese claims data

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