RANKL regulates male reproductive function

There are few treatments for male infertility. Here, the authors show that the receptor activator of NF-κB ligand (RANKL) signalling pathway has important functions in sperm production and maturation, improves fertility in male mice and shows potential as a male infertility target.

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Autores principales:	Martin Blomberg Jensen, Christine Hjorth Andreassen, Anne Jørgensen, John Erik Nielsen, Li Juel Mortensen, Ida Marie Boisen, Peter Schwarz, Jorma Toppari, Roland Baron, Beate Lanske, Anders Juul
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/449cfadef8624b1985ea27a0de2d651b
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spelling	oai:doaj.org-article:449cfadef8624b1985ea27a0de2d651b2021-12-02T13:39:46ZRANKL regulates male reproductive function10.1038/s41467-021-22734-82041-1723https://doaj.org/article/449cfadef8624b1985ea27a0de2d651b2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22734-8https://doaj.org/toc/2041-1723There are few treatments for male infertility. Here, the authors show that the receptor activator of NF-κB ligand (RANKL) signalling pathway has important functions in sperm production and maturation, improves fertility in male mice and shows potential as a male infertility target.Martin Blomberg JensenChristine Hjorth AndreassenAnne JørgensenJohn Erik NielsenLi Juel MortensenIda Marie BoisenPeter SchwarzJorma ToppariRoland BaronBeate LanskeAnders JuulNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Martin Blomberg Jensen Christine Hjorth Andreassen Anne Jørgensen John Erik Nielsen Li Juel Mortensen Ida Marie Boisen Peter Schwarz Jorma Toppari Roland Baron Beate Lanske Anders Juul RANKL regulates male reproductive function
description	There are few treatments for male infertility. Here, the authors show that the receptor activator of NF-κB ligand (RANKL) signalling pathway has important functions in sperm production and maturation, improves fertility in male mice and shows potential as a male infertility target.
format	article
author	Martin Blomberg Jensen Christine Hjorth Andreassen Anne Jørgensen John Erik Nielsen Li Juel Mortensen Ida Marie Boisen Peter Schwarz Jorma Toppari Roland Baron Beate Lanske Anders Juul
author_facet	Martin Blomberg Jensen Christine Hjorth Andreassen Anne Jørgensen John Erik Nielsen Li Juel Mortensen Ida Marie Boisen Peter Schwarz Jorma Toppari Roland Baron Beate Lanske Anders Juul
author_sort	Martin Blomberg Jensen
title	RANKL regulates male reproductive function
title_short	RANKL regulates male reproductive function
title_full	RANKL regulates male reproductive function
title_fullStr	RANKL regulates male reproductive function
title_full_unstemmed	RANKL regulates male reproductive function
title_sort	rankl regulates male reproductive function
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/449cfadef8624b1985ea27a0de2d651b
work_keys_str_mv	AT martinblombergjensen ranklregulatesmalereproductivefunction AT christinehjorthandreassen ranklregulatesmalereproductivefunction AT annejørgensen ranklregulatesmalereproductivefunction AT johneriknielsen ranklregulatesmalereproductivefunction AT lijuelmortensen ranklregulatesmalereproductivefunction AT idamarieboisen ranklregulatesmalereproductivefunction AT peterschwarz ranklregulatesmalereproductivefunction AT jormatoppari ranklregulatesmalereproductivefunction AT rolandbaron ranklregulatesmalereproductivefunction AT beatelanske ranklregulatesmalereproductivefunction AT andersjuul ranklregulatesmalereproductivefunction
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RANKL regulates male reproductive function

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