The adaptive landscape of a metallo-enzyme is shaped by environment-dependent epistasis
The metaphor of an adaptive landscape is presented quantitatively by looking at molecular adaptations and their catalytic consequences in a recently evolved bacterial enzyme. The study identifies both genotype-by-environment interactions and environment-dependent epistasis as factors that can alter...
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Main Authors: | Dave W. Anderson, Florian Baier, Gloria Yang, Nobuhiko Tokuriki |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/44a0b8b6361c40a7b937ffbaa42ff7e2 |
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