Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites

Ghaly et al. use cassette recombination sites to predict the origins of antibiotic resistance cassettes spread by mobile integrons. They find that more than a quarter of all resistance cassettes have recombination sites that are structurally conserved among one of three taxa (Xanthomonadales, Spiroc...

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Autores principales: Timothy M. Ghaly, Sasha G. Tetu, Michael R. Gillings
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/44ae82c6ec62489e911372a9f7f6b3f4
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spelling oai:doaj.org-article:44ae82c6ec62489e911372a9f7f6b3f42021-12-02T18:50:46ZPredicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites10.1038/s42003-021-02489-02399-3642https://doaj.org/article/44ae82c6ec62489e911372a9f7f6b3f42021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02489-0https://doaj.org/toc/2399-3642Ghaly et al. use cassette recombination sites to predict the origins of antibiotic resistance cassettes spread by mobile integrons. They find that more than a quarter of all resistance cassettes have recombination sites that are structurally conserved among one of three taxa (Xanthomonadales, Spirochaetes and Vibrionales).Timothy M. GhalySasha G. TetuMichael R. GillingsNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Timothy M. Ghaly
Sasha G. Tetu
Michael R. Gillings
Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
description Ghaly et al. use cassette recombination sites to predict the origins of antibiotic resistance cassettes spread by mobile integrons. They find that more than a quarter of all resistance cassettes have recombination sites that are structurally conserved among one of three taxa (Xanthomonadales, Spirochaetes and Vibrionales).
format article
author Timothy M. Ghaly
Sasha G. Tetu
Michael R. Gillings
author_facet Timothy M. Ghaly
Sasha G. Tetu
Michael R. Gillings
author_sort Timothy M. Ghaly
title Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
title_short Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
title_full Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
title_fullStr Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
title_full_unstemmed Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
title_sort predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attc sites
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/44ae82c6ec62489e911372a9f7f6b3f4
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AT sashagtetu predictingthetaxonomicandenvironmentalsourcesofintegrongenecassettesusingstructuralandsequencehomologyofattcsites
AT michaelrgillings predictingthetaxonomicandenvironmentalsourcesofintegrongenecassettesusingstructuralandsequencehomologyofattcsites
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