Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
Ghaly et al. use cassette recombination sites to predict the origins of antibiotic resistance cassettes spread by mobile integrons. They find that more than a quarter of all resistance cassettes have recombination sites that are structurally conserved among one of three taxa (Xanthomonadales, Spiroc...
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Nature Portfolio
2021
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oai:doaj.org-article:44ae82c6ec62489e911372a9f7f6b3f42021-12-02T18:50:46ZPredicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites10.1038/s42003-021-02489-02399-3642https://doaj.org/article/44ae82c6ec62489e911372a9f7f6b3f42021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02489-0https://doaj.org/toc/2399-3642Ghaly et al. use cassette recombination sites to predict the origins of antibiotic resistance cassettes spread by mobile integrons. They find that more than a quarter of all resistance cassettes have recombination sites that are structurally conserved among one of three taxa (Xanthomonadales, Spirochaetes and Vibrionales).Timothy M. GhalySasha G. TetuMichael R. GillingsNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-8 (2021) |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Timothy M. Ghaly Sasha G. Tetu Michael R. Gillings Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites |
description |
Ghaly et al. use cassette recombination sites to predict the origins of antibiotic resistance cassettes spread by mobile integrons. They find that more than a quarter of all resistance cassettes have recombination sites that are structurally conserved among one of three taxa (Xanthomonadales, Spirochaetes and Vibrionales). |
format |
article |
author |
Timothy M. Ghaly Sasha G. Tetu Michael R. Gillings |
author_facet |
Timothy M. Ghaly Sasha G. Tetu Michael R. Gillings |
author_sort |
Timothy M. Ghaly |
title |
Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites |
title_short |
Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites |
title_full |
Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites |
title_fullStr |
Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites |
title_full_unstemmed |
Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites |
title_sort |
predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attc sites |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/44ae82c6ec62489e911372a9f7f6b3f4 |
work_keys_str_mv |
AT timothymghaly predictingthetaxonomicandenvironmentalsourcesofintegrongenecassettesusingstructuralandsequencehomologyofattcsites AT sashagtetu predictingthetaxonomicandenvironmentalsourcesofintegrongenecassettesusingstructuralandsequencehomologyofattcsites AT michaelrgillings predictingthetaxonomicandenvironmentalsourcesofintegrongenecassettesusingstructuralandsequencehomologyofattcsites |
_version_ |
1718377499872722944 |