Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites

Ghaly et al. use cassette recombination sites to predict the origins of antibiotic resistance cassettes spread by mobile integrons. They find that more than a quarter of all resistance cassettes have recombination sites that are structurally conserved among one of three taxa (Xanthomonadales, Spiroc...

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Main Authors:	Timothy M. Ghaly, Sasha G. Tetu, Michael R. Gillings
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Biology (General) QH301-705.5
Online Access:	https://doaj.org/article/44ae82c6ec62489e911372a9f7f6b3f4
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id	oai:doaj.org-article:44ae82c6ec62489e911372a9f7f6b3f4
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spelling	oai:doaj.org-article:44ae82c6ec62489e911372a9f7f6b3f42021-12-02T18:50:46ZPredicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites10.1038/s42003-021-02489-02399-3642https://doaj.org/article/44ae82c6ec62489e911372a9f7f6b3f42021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02489-0https://doaj.org/toc/2399-3642Ghaly et al. use cassette recombination sites to predict the origins of antibiotic resistance cassettes spread by mobile integrons. They find that more than a quarter of all resistance cassettes have recombination sites that are structurally conserved among one of three taxa (Xanthomonadales, Spirochaetes and Vibrionales).Timothy M. GhalySasha G. TetuMichael R. GillingsNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Timothy M. Ghaly Sasha G. Tetu Michael R. Gillings Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
description	Ghaly et al. use cassette recombination sites to predict the origins of antibiotic resistance cassettes spread by mobile integrons. They find that more than a quarter of all resistance cassettes have recombination sites that are structurally conserved among one of three taxa (Xanthomonadales, Spirochaetes and Vibrionales).
format	article
author	Timothy M. Ghaly Sasha G. Tetu Michael R. Gillings
author_facet	Timothy M. Ghaly Sasha G. Tetu Michael R. Gillings
author_sort	Timothy M. Ghaly
title	Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
title_short	Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
title_full	Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
title_fullStr	Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
title_full_unstemmed	Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites
title_sort	predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attc sites
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/44ae82c6ec62489e911372a9f7f6b3f4
work_keys_str_mv	AT timothymghaly predictingthetaxonomicandenvironmentalsourcesofintegrongenecassettesusingstructuralandsequencehomologyofattcsites AT sashagtetu predictingthetaxonomicandenvironmentalsourcesofintegrongenecassettesusingstructuralandsequencehomologyofattcsites AT michaelrgillings predictingthetaxonomicandenvironmentalsourcesofintegrongenecassettesusingstructuralandsequencehomologyofattcsites
_version_	1718377499872722944

Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites

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