Synthetic extracellular matrices with tailored adhesiveness and degradability support lumen formation during angiogenic sprouting
Current tissue engineering strategies lack materials that promote angiogenesis. Here the authors develop a microfluidic in vitro model in which chemokine-guided endothelial cell sprouting into a tunable hydrogel is followed by the formation of perfusable lumens to determine the material properties t...
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Autores principales: | Jifeng Liu, Hongyan Long, Dagmar Zeuschner, Andreas F. B. Räder, William J. Polacheck, Horst Kessler, Lydia Sorokin, Britta Trappmann |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/44b2977179d84acea256312132cf8fe7 |
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