Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction

Abstract In Poland the issue of microsomic body structure (micro-SBS) and macrosomic body structure (macro-SBS) has so far been overlooked. Up until now only a small amount of data have been published, most often as an overview of the problem. The current study was designed to investigate the co-occ...

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Autores principales: Lidia Perenc, Agnieszka Guzik, Justyna Podgórska-Bednarz, Mariusz Drużbicki
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/44b9eeb0f2a643e3910eb0b269604bf3
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spelling oai:doaj.org-article:44b9eeb0f2a643e3910eb0b269604bf32021-12-02T11:39:44ZMicrosomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction10.1038/s41598-021-85587-72045-2322https://doaj.org/article/44b9eeb0f2a643e3910eb0b269604bf32021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-85587-7https://doaj.org/toc/2045-2322Abstract In Poland the issue of microsomic body structure (micro-SBS) and macrosomic body structure (macro-SBS) has so far been overlooked. Up until now only a small amount of data have been published, most often as an overview of the problem. The current study was designed to investigate the co-occurrence of microsomic/macrosomic body structure (micro/macro-SBS) and congenital nervous system disorders or neurological syndromes with symptoms visible from infancy, based on essential data acquired during admission procedures at a neurological rehabilitation ward for children and adolescents. The study applied a retrospective analysis of data collected during hospitalization of 327 children and adolescents, aged 4–18 years who had been affected since infancy by congenital disorders of the nervous system and/or neurological syndromes associated with a minimum of one neurodysfunction. To identify subjects with microsomic or macrosomic body structure in the group of children and adolescents, the adopted criteria took into account z-score values for body height (z-score Ht), body weight (z-score Wt), head circumference (z-score HC), BMI (z-score BMI) and head circumference index (z-score HCI). The rates of micro/macro-SBS in the study group amounted to 7.3% and 0.6%, respectively. The findings show a more frequent co-occurrence of, as well as statistically significant correlations between, micro/macro-SBS and type of spasticity (cerebral palsy) (p = 0.024) as well as hydrocephalus not treated surgically (p < 0.001). Macro-SBS was found to more frequently co-occur with hemiplegia and hydrocephalus not treated surgically.Lidia PerencAgnieszka GuzikJustyna Podgórska-BednarzMariusz DrużbickiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Lidia Perenc
Agnieszka Guzik
Justyna Podgórska-Bednarz
Mariusz Drużbicki
Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
description Abstract In Poland the issue of microsomic body structure (micro-SBS) and macrosomic body structure (macro-SBS) has so far been overlooked. Up until now only a small amount of data have been published, most often as an overview of the problem. The current study was designed to investigate the co-occurrence of microsomic/macrosomic body structure (micro/macro-SBS) and congenital nervous system disorders or neurological syndromes with symptoms visible from infancy, based on essential data acquired during admission procedures at a neurological rehabilitation ward for children and adolescents. The study applied a retrospective analysis of data collected during hospitalization of 327 children and adolescents, aged 4–18 years who had been affected since infancy by congenital disorders of the nervous system and/or neurological syndromes associated with a minimum of one neurodysfunction. To identify subjects with microsomic or macrosomic body structure in the group of children and adolescents, the adopted criteria took into account z-score values for body height (z-score Ht), body weight (z-score Wt), head circumference (z-score HC), BMI (z-score BMI) and head circumference index (z-score HCI). The rates of micro/macro-SBS in the study group amounted to 7.3% and 0.6%, respectively. The findings show a more frequent co-occurrence of, as well as statistically significant correlations between, micro/macro-SBS and type of spasticity (cerebral palsy) (p = 0.024) as well as hydrocephalus not treated surgically (p < 0.001). Macro-SBS was found to more frequently co-occur with hemiplegia and hydrocephalus not treated surgically.
format article
author Lidia Perenc
Agnieszka Guzik
Justyna Podgórska-Bednarz
Mariusz Drużbicki
author_facet Lidia Perenc
Agnieszka Guzik
Justyna Podgórska-Bednarz
Mariusz Drużbicki
author_sort Lidia Perenc
title Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title_short Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title_full Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title_fullStr Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title_full_unstemmed Microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
title_sort microsomic and macrosomic body structure in children and adolescents affected by syndromes or diseases associated with neurodysfunction
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/44b9eeb0f2a643e3910eb0b269604bf3
work_keys_str_mv AT lidiaperenc microsomicandmacrosomicbodystructureinchildrenandadolescentsaffectedbysyndromesordiseasesassociatedwithneurodysfunction
AT agnieszkaguzik microsomicandmacrosomicbodystructureinchildrenandadolescentsaffectedbysyndromesordiseasesassociatedwithneurodysfunction
AT justynapodgorskabednarz microsomicandmacrosomicbodystructureinchildrenandadolescentsaffectedbysyndromesordiseasesassociatedwithneurodysfunction
AT mariuszdruzbicki microsomicandmacrosomicbodystructureinchildrenandadolescentsaffectedbysyndromesordiseasesassociatedwithneurodysfunction
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