Quantitative real-time imaging of glutathione

Fluorescent sensors for small biomolecules are needed to shed insight into real-time cellular processes. Here the authors develop RealThiol, a sensor that can quantitatively monitor glutathione dynamics in living cells, and measure increased antioxidant capability of activated neurons and glutathion...

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Autores principales:	Xiqian Jiang, Jianwei Chen, Aleksandar Bajić, Chengwei Zhang, Xianzhou Song, Shaina L. Carroll, Zhao-Lin Cai, Meiling Tang, Mingshan Xue, Ninghui Cheng, Christian P. Schaaf, Feng Li, Kevin R. MacKenzie, Allan Chris M. Ferreon, Fan Xia, Meng C. Wang, Mirjana Maletić-Savatić, Jin Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/44beb87514aa4446b912f029a49d9432
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spelling	oai:doaj.org-article:44beb87514aa4446b912f029a49d94322021-12-02T14:41:09ZQuantitative real-time imaging of glutathione10.1038/ncomms160872041-1723https://doaj.org/article/44beb87514aa4446b912f029a49d94322017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms16087https://doaj.org/toc/2041-1723Fluorescent sensors for small biomolecules are needed to shed insight into real-time cellular processes. Here the authors develop RealThiol, a sensor that can quantitatively monitor glutathione dynamics in living cells, and measure increased antioxidant capability of activated neurons and glutathione changes during ferroptosis.Xiqian JiangJianwei ChenAleksandar BajićChengwei ZhangXianzhou SongShaina L. CarrollZhao-Lin CaiMeiling TangMingshan XueNinghui ChengChristian P. SchaafFeng LiKevin R. MacKenzieAllan Chris M. FerreonFan XiaMeng C. WangMirjana Maletić-SavatićJin WangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiqian Jiang Jianwei Chen Aleksandar Bajić Chengwei Zhang Xianzhou Song Shaina L. Carroll Zhao-Lin Cai Meiling Tang Mingshan Xue Ninghui Cheng Christian P. Schaaf Feng Li Kevin R. MacKenzie Allan Chris M. Ferreon Fan Xia Meng C. Wang Mirjana Maletić-Savatić Jin Wang Quantitative real-time imaging of glutathione
description	Fluorescent sensors for small biomolecules are needed to shed insight into real-time cellular processes. Here the authors develop RealThiol, a sensor that can quantitatively monitor glutathione dynamics in living cells, and measure increased antioxidant capability of activated neurons and glutathione changes during ferroptosis.
format	article
author	Xiqian Jiang Jianwei Chen Aleksandar Bajić Chengwei Zhang Xianzhou Song Shaina L. Carroll Zhao-Lin Cai Meiling Tang Mingshan Xue Ninghui Cheng Christian P. Schaaf Feng Li Kevin R. MacKenzie Allan Chris M. Ferreon Fan Xia Meng C. Wang Mirjana Maletić-Savatić Jin Wang
author_facet	Xiqian Jiang Jianwei Chen Aleksandar Bajić Chengwei Zhang Xianzhou Song Shaina L. Carroll Zhao-Lin Cai Meiling Tang Mingshan Xue Ninghui Cheng Christian P. Schaaf Feng Li Kevin R. MacKenzie Allan Chris M. Ferreon Fan Xia Meng C. Wang Mirjana Maletić-Savatić Jin Wang
author_sort	Xiqian Jiang
title	Quantitative real-time imaging of glutathione
title_short	Quantitative real-time imaging of glutathione
title_full	Quantitative real-time imaging of glutathione
title_fullStr	Quantitative real-time imaging of glutathione
title_full_unstemmed	Quantitative real-time imaging of glutathione
title_sort	quantitative real-time imaging of glutathione
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/44beb87514aa4446b912f029a49d9432
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_version_	1718389985693925376

Quantitative real-time imaging of glutathione

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