Plaque psoriasis in children and adolescents – the role of etanercept
Federica Ricceri, Lara Tripo, Leonardo Pescitelli, Francesca PrignanoDivision of Clinical, Preventive and Oncology Dermatology, Department of Critical Care Medicine and Surgery, University of Florence, Florence, ItalyBackground: Childhood-onset psoriasis affects approximately one-third of the psoria...
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Dove Medical Press
2012
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oai:doaj.org-article:44c512d1a2ff4649a1532b278205bfd62021-12-02T01:49:21ZPlaque psoriasis in children and adolescents – the role of etanercept2230-326Xhttps://doaj.org/article/44c512d1a2ff4649a1532b278205bfd62012-06-01T00:00:00Zhttp://www.dovepress.com/plaque-psoriasis-in-children-and-adolescents-ndash-the-role-of-etanerc-a10072https://doaj.org/toc/2230-326XFederica Ricceri, Lara Tripo, Leonardo Pescitelli, Francesca PrignanoDivision of Clinical, Preventive and Oncology Dermatology, Department of Critical Care Medicine and Surgery, University of Florence, Florence, ItalyBackground: Childhood-onset psoriasis affects approximately one-third of the psoriatic population. Among many potential treatments of childhood psoriasis, biological agents are emerging as a valuable option in the management of this disease. In Europe, etanercept has recently been approved for children aged 6 years and over. Data from a well-designed clinical trial indicate that in children, etanercept effectively reduces psoriasis symptoms, with beneficial effects evident as early as 4 weeks after the onset of therapy. The treatment is generally well tolerated; mild injection site reactions are the most common adverse events reported in the literature. Published data of etanercept use in children show promising results, but further clinical studies are necessary to confirm its long-term efficacy and safety.Keywords: pediatric psoriasis, anti-TNF-α, etanerceptRicceri FTripo LPescitelli LPrignano FDove Medical PressarticleDermatologyRL1-803ENPsoriasis: Targets and Therapy, Vol 2012, Iss default, Pp 25-28 (2012) |
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DOAJ |
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DOAJ |
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EN |
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Dermatology RL1-803 |
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Dermatology RL1-803 Ricceri F Tripo L Pescitelli L Prignano F Plaque psoriasis in children and adolescents – the role of etanercept |
| description |
Federica Ricceri, Lara Tripo, Leonardo Pescitelli, Francesca PrignanoDivision of Clinical, Preventive and Oncology Dermatology, Department of Critical Care Medicine and Surgery, University of Florence, Florence, ItalyBackground: Childhood-onset psoriasis affects approximately one-third of the psoriatic population. Among many potential treatments of childhood psoriasis, biological agents are emerging as a valuable option in the management of this disease. In Europe, etanercept has recently been approved for children aged 6 years and over. Data from a well-designed clinical trial indicate that in children, etanercept effectively reduces psoriasis symptoms, with beneficial effects evident as early as 4 weeks after the onset of therapy. The treatment is generally well tolerated; mild injection site reactions are the most common adverse events reported in the literature. Published data of etanercept use in children show promising results, but further clinical studies are necessary to confirm its long-term efficacy and safety.Keywords: pediatric psoriasis, anti-TNF-α, etanercept |
| format |
article |
| author |
Ricceri F Tripo L Pescitelli L Prignano F |
| author_facet |
Ricceri F Tripo L Pescitelli L Prignano F |
| author_sort |
Ricceri F |
| title |
Plaque psoriasis in children and adolescents – the role of etanercept |
| title_short |
Plaque psoriasis in children and adolescents – the role of etanercept |
| title_full |
Plaque psoriasis in children and adolescents – the role of etanercept |
| title_fullStr |
Plaque psoriasis in children and adolescents – the role of etanercept |
| title_full_unstemmed |
Plaque psoriasis in children and adolescents – the role of etanercept |
| title_sort |
plaque psoriasis in children and adolescents – the role of etanercept |
| publisher |
Dove Medical Press |
| publishDate |
2012 |
| url |
https://doaj.org/article/44c512d1a2ff4649a1532b278205bfd6 |
| work_keys_str_mv |
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| _version_ |
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