E-cigarettes can emit formaldehyde at high levels under conditions that have been reported to be non-averse to users

Abstract E-cigarette aerosol emission studies typically focus on benchmarking toxicant levels versus those of cigarettes. However, such studies do not fully account for the distinct chemical makeup of e-liquids and their unique properties. These approaches often conclude that there are fewer and low...

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Autores principales:	James C. Salamanca, Jiries Meehan-Atrash, Shawna Vreeke, Jorge O. Escobedo, David H. Peyton, Robert M. Strongin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/44cc1aadddfd461f862839abda7c0890
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spelling	oai:doaj.org-article:44cc1aadddfd461f862839abda7c08902021-12-02T15:08:01ZE-cigarettes can emit formaldehyde at high levels under conditions that have been reported to be non-averse to users10.1038/s41598-018-25907-62045-2322https://doaj.org/article/44cc1aadddfd461f862839abda7c08902018-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-25907-6https://doaj.org/toc/2045-2322Abstract E-cigarette aerosol emission studies typically focus on benchmarking toxicant levels versus those of cigarettes. However, such studies do not fully account for the distinct chemical makeup of e-liquids and their unique properties. These approaches often conclude that there are fewer and lower levels of toxins produced by e-cigarettes than by cigarettes. In 2015, we reported the discovery of new hemiacetals derived from the reaction of formaldehyde and the e-liquid solvents. The main finding was that they constituted a significant proportion of potentially undetected formaldehyde. Moreover, unlike gaseous formaldehyde, the hemiacetals reside in the aerosol particulate phase, and thus are capable of delivering formaldehyde more deeply into the lungs. However, the findings were criticized by those claiming that some of the results were obtained under conditions that are averse to vapers. A “reinvestigation” of our study was recently published addressing this latter issue. However, this reinvestigation ignored major details, including no mention of the formaldehyde hemiacetals. Herein, we isolated both gaseous formaldehyde and formaldehyde hemiacetals at an intermediate power level claimed, in the “reinvestigation”, to be relevant to “non-averse,” “normal” usage. The results were that both gaseous formaldehyde and formaldehyde from hemiacetals were produced at levels above OSHA workplace limits.James C. SalamancaJiries Meehan-AtrashShawna VreekeJorge O. EscobedoDavid H. PeytonRobert M. StronginNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-6 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q James C. Salamanca Jiries Meehan-Atrash Shawna Vreeke Jorge O. Escobedo David H. Peyton Robert M. Strongin E-cigarettes can emit formaldehyde at high levels under conditions that have been reported to be non-averse to users
description	Abstract E-cigarette aerosol emission studies typically focus on benchmarking toxicant levels versus those of cigarettes. However, such studies do not fully account for the distinct chemical makeup of e-liquids and their unique properties. These approaches often conclude that there are fewer and lower levels of toxins produced by e-cigarettes than by cigarettes. In 2015, we reported the discovery of new hemiacetals derived from the reaction of formaldehyde and the e-liquid solvents. The main finding was that they constituted a significant proportion of potentially undetected formaldehyde. Moreover, unlike gaseous formaldehyde, the hemiacetals reside in the aerosol particulate phase, and thus are capable of delivering formaldehyde more deeply into the lungs. However, the findings were criticized by those claiming that some of the results were obtained under conditions that are averse to vapers. A “reinvestigation” of our study was recently published addressing this latter issue. However, this reinvestigation ignored major details, including no mention of the formaldehyde hemiacetals. Herein, we isolated both gaseous formaldehyde and formaldehyde hemiacetals at an intermediate power level claimed, in the “reinvestigation”, to be relevant to “non-averse,” “normal” usage. The results were that both gaseous formaldehyde and formaldehyde from hemiacetals were produced at levels above OSHA workplace limits.
format	article
author	James C. Salamanca Jiries Meehan-Atrash Shawna Vreeke Jorge O. Escobedo David H. Peyton Robert M. Strongin
author_facet	James C. Salamanca Jiries Meehan-Atrash Shawna Vreeke Jorge O. Escobedo David H. Peyton Robert M. Strongin
author_sort	James C. Salamanca
title	E-cigarettes can emit formaldehyde at high levels under conditions that have been reported to be non-averse to users
title_short	E-cigarettes can emit formaldehyde at high levels under conditions that have been reported to be non-averse to users
title_full	E-cigarettes can emit formaldehyde at high levels under conditions that have been reported to be non-averse to users
title_fullStr	E-cigarettes can emit formaldehyde at high levels under conditions that have been reported to be non-averse to users
title_full_unstemmed	E-cigarettes can emit formaldehyde at high levels under conditions that have been reported to be non-averse to users
title_sort	e-cigarettes can emit formaldehyde at high levels under conditions that have been reported to be non-averse to users
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/44cc1aadddfd461f862839abda7c0890
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E-cigarettes can emit formaldehyde at high levels under conditions that have been reported to be non-averse to users

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