Disruption of the Toxoplasma gondii parasitophorous vacuole by IFNgamma-inducible immunity-related GTPases (IRG proteins) triggers necrotic cell death.
Toxoplasma gondii is a natural intracellular protozoal pathogen of mice and other small mammals. After infection, the parasite replicates freely in many cell types (tachyzoite stage) before undergoing a phase transition and encysting in brain and muscle (bradyzoite stage). In the mouse, early immune...
Enregistré dans:
Auteurs principaux: | Yang O Zhao, Aliaksandr Khaminets, Julia P Hunn, Jonathan C Howard |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2009
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/44cf9c89c4704ba08ad7a4354bd3a5f4 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Rhoptry kinase protein 39 (ROP39) is a novel factor that recruits host mitochondria to the parasitophorous vacuole of Toxoplasma gondii
par: Junpei Fukumoto, et autres
Publié: (2021) -
<named-content content-type="genus-species">Toxoplasma gondii</named-content> Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Regulate Maturation of the Cyst Wall
par: Rebekah B. Guevara, et autres
Publié: (2020) -
Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole.
par: Iset Medina Vera, et autres
Publié: (2011) -
<named-content content-type="genus-species">Toxoplasma gondii</named-content> Parasitophorous Vacuole Membrane-Associated Dense Granule Proteins Orchestrate Chronic Infection and GRA12 Underpins Resistance to Host Gamma Interferon
par: Barbara A. Fox, et autres
Publié: (2019) -
Coimmunoprecipitation with MYR1 Identifies Three Additional Proteins within the <named-content content-type="genus-species">Toxoplasma gondii</named-content> Parasitophorous Vacuole Required for Translocation of Dense Granule Effectors into Host Cells
par: Alicja M. Cygan, et autres
Publié: (2020)