An intraosseous giant cell granuloma: An uncommon presentation

The giant cell granuloma is an identical reactive lesion which is mostly progressive in nature. The clinical behavior of these lesions varies from indolent to aggressive variant. The central form of giant cell granuloma involves the craniofacial bone, followed by long bones of hands and feet. These...

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Autores principales: V Ravi Pavan, Vijayanirmala Subramani, S Senthoor Pandian, G V V Giri
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Lenguaje:EN
Publicado: Wolters Kluwer Medknow Publications 2021
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spelling oai:doaj.org-article:44d3fce82cf44f5aa19bfcff162bb7b62021-11-19T12:15:54ZAn intraosseous giant cell granuloma: An uncommon presentation0975-740610.4103/jpbs.jpbs_154_21https://doaj.org/article/44d3fce82cf44f5aa19bfcff162bb7b62021-01-01T00:00:00Zhttp://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=6;spage=1741;epage=1743;aulast=Pavanhttps://doaj.org/toc/0975-7406The giant cell granuloma is an identical reactive lesion which is mostly progressive in nature. The clinical behavior of these lesions varies from indolent to aggressive variant. The central form of giant cell granuloma involves the craniofacial bone, followed by long bones of hands and feet. These lesions are usually asymptomatic lesions and are discovered incidentally during routine radiographic examination. Radiograph features reveal multilocular jaw lesions, generally anterior to the first molar regions. Histologically, the lesion shows proliferating spindle-shaped stromal cells in a fibrovascular connective tissue stroma, which characteristically contains multiple multinucleated giant cells. Hemorrhage and hemosiderin pigmentations are often seen in tumor. Central giant cell granuloma is often confused with giant cell tumor of bone histologically. Here, we report a young male who was found to have large central giant cell granuloma in the anterior part of the mandible. The surgical treatment approach of central giant cell granuloma is discussed in this article.V Ravi PavanVijayanirmala SubramaniS Senthoor PandianG V V GiriWolters Kluwer Medknow Publicationsarticlegiant cells and peripheral ostectomyosteolytic lesionprogressivePharmacy and materia medicaRS1-441Analytical chemistryQD71-142ENJournal of Pharmacy and Bioallied Sciences, Vol 13, Iss 6, Pp 1741-1743 (2021)
institution DOAJ
collection DOAJ
language EN
topic giant cells and peripheral ostectomy
osteolytic lesion
progressive
Pharmacy and materia medica
RS1-441
Analytical chemistry
QD71-142
spellingShingle giant cells and peripheral ostectomy
osteolytic lesion
progressive
Pharmacy and materia medica
RS1-441
Analytical chemistry
QD71-142
V Ravi Pavan
Vijayanirmala Subramani
S Senthoor Pandian
G V V Giri
An intraosseous giant cell granuloma: An uncommon presentation
description The giant cell granuloma is an identical reactive lesion which is mostly progressive in nature. The clinical behavior of these lesions varies from indolent to aggressive variant. The central form of giant cell granuloma involves the craniofacial bone, followed by long bones of hands and feet. These lesions are usually asymptomatic lesions and are discovered incidentally during routine radiographic examination. Radiograph features reveal multilocular jaw lesions, generally anterior to the first molar regions. Histologically, the lesion shows proliferating spindle-shaped stromal cells in a fibrovascular connective tissue stroma, which characteristically contains multiple multinucleated giant cells. Hemorrhage and hemosiderin pigmentations are often seen in tumor. Central giant cell granuloma is often confused with giant cell tumor of bone histologically. Here, we report a young male who was found to have large central giant cell granuloma in the anterior part of the mandible. The surgical treatment approach of central giant cell granuloma is discussed in this article.
format article
author V Ravi Pavan
Vijayanirmala Subramani
S Senthoor Pandian
G V V Giri
author_facet V Ravi Pavan
Vijayanirmala Subramani
S Senthoor Pandian
G V V Giri
author_sort V Ravi Pavan
title An intraosseous giant cell granuloma: An uncommon presentation
title_short An intraosseous giant cell granuloma: An uncommon presentation
title_full An intraosseous giant cell granuloma: An uncommon presentation
title_fullStr An intraosseous giant cell granuloma: An uncommon presentation
title_full_unstemmed An intraosseous giant cell granuloma: An uncommon presentation
title_sort intraosseous giant cell granuloma: an uncommon presentation
publisher Wolters Kluwer Medknow Publications
publishDate 2021
url https://doaj.org/article/44d3fce82cf44f5aa19bfcff162bb7b6
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